Was a pleasure to report on our synthetic immunology approach and how we use synthetic cells to improve immunotherapy 🎧
Building tissues from the bottom up!
In Advanced Healthcare Materials @wiley.com, @ostaufer.bsky.social and co-authors show synthetic cells forming lymph-node-like tissues that host immune cells -towards building synthetic organs.
doi.org/10.1002/adhm...
#academicsky 🧪
Excited to share our new @pnas.org paper! We used reconstitution approaches and synthetic cells to uncover what drives bispecific T cell engagers efficiency. This helps future #immunotherapy design and demonstrates the potential of synthetic cells in #immunoengineering:
www.pnas.org/doi/10.1073/...
Congrats to Saarbrücken researchers!
Prof. Karin Jacobs, Prof. Franziska Lautenschläger & @ostaufer.bsky.social join the Max Planck School Matter to Life as Fellows, strengthening biophysics & soft matter research in Germany.
#academicsky #science
New paper out in NatureComm: We built synthetic immune cells that self-assemble with cancer cells into hybrid tumoroids, enabling bottom-up reconstruction of the tumor immune microenvironment.
rdcu.be/eUmRM
@leibnizinm.bsky.social
New paper from the Staufer Lab - Immuno Materials, a group that seeks to build immunity from the bottom-up
Bispecific T cell engagers (TcEs) link T cell receptors to tumor-associated antigens
on cancer cells, forming cytotoxic immunological synapses (IS)...
www.pnas.org
Synthetic cells have emerged as a novel biomimetic approach for fundamental research and therapeutic interventions. T cell activating synthetic cells are able to form 3D tissue-like structures by sel....
Excited to share our new @pnas.org paper! We used reconstitution approaches and synthetic cells to uncover what drives bispecific T cell engagers efficiency. This helps future #immunotherapy design and demonstrates the potential of synthetic cells in #immunoengineering:
www.pnas.org/doi/10.1073/...
Wie künstliche Zellen den #Krebs besiegen könnten.
Darüber spricht @ostaufer.bsky.social vom @leibnizinm.bsky.social in der neuen Folge von #TonspurWissen, dem #Podcast von Leibniz-Gemeinschaft und Rheinischer Post.
🎧 👉 pod.fo/e/388f21
#Biologie #Medizin #Immuntherapie #Gesundheit #Wissenschaftsjahr
Very happy to have you onboard Marion!
Bispecific T cell engagers (TcEs) link T cell receptors to tumor-associated antigens
on cancer cells, forming cytotoxic immunological synapses (IS)...
New paper out! Would you like to fluorescently label the plasma membrane in live, fixed or permeabilized cells? I tested different lipid structures and labelling approaches to decide what makes a good membrane labelling probe for such imaging experiments!
www.biorxiv.org/content/10.1...
Apply now to join my group as a postdoctoral Fellow at @imperialcollege
We are supporting applications for:
- Imperial College Research Fellowship
-Marie Skłodowska-Curie Postdoctoral Fellowships
Get in touch: continilab.com
#SoftMatter, #CellMimicry #polymerchemistry
🌱 New beginnings, fresh faces!
As our pilot phase wraps up, the school is ready to grow and thrive. We’re thrilled to welcome 18 new fellows to the #MatterToLife Faculty 🎉 Each brings exciting perspectives from across interdisciplinary research. mattertolife.maxplanckschools.org/355008/new-f...
www.biorxiv.org
Labeling the plasma membrane for advanced imaging remains a significant challenge. For time-lapse live cell imaging, probe internalization and photobleaching are major limitations affecting most membr...
We are super excited to announce that Marion has joined our #MSCA-DN to work in the @ostaufer.bsky.social lab.
The project will focus on the development of #SyntheticCell models that mimic #Age-RelatedDiseases. More details: www.comeincell.org/dc04-synthet...
Welcome Marion! #HorizonEurope
