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New paper from the Staufer Lab - Immuno Materials, a group that seeks to build immunity from the bottom-up
Jun 2, 2025
European Synthetic Cell Initiative
Excited to share our new @pnas.org paper! We used reconstitution approaches and synthetic cells to uncover what drives bispecific T cell engagers efficiency. This helps future #immunotherapy design and demonstrates the potential of synthetic cells in #immunoengineering: www.pnas.org/doi/10.1073/...
May 31, 2025
Bispecific T cell engagers (TcEs) link T cell receptors to tumor-associated antigens on cancer cells, forming cytotoxic immunological synapses (IS)...
www.pnas.org
Solution structure and synaptic analyses reveal determinants of bispecific T cell engager potency | PNAS
Oskar Staufer