Excited to share our new @pnas.org paper! We used reconstitution approaches and synthetic cells to uncover what drives bispecific T cell engagers efficiency. This helps future #immunotherapy design and demonstrates the potential of synthetic cells in #immunoengineering:
www.pnas.org/doi/10.1073/...
Bispecific T cell engagers (TcEs) link T cell receptors to tumor-associated antigens
on cancer cells, forming cytotoxic immunological synapses (IS)...