Inlay

Profile

Neuroscientist at the Paris Brain Institute / www.dejuansanzlab.org / ERC / FENS-Kavli Scholar / Young Academy of Spain / CNRS

Jaime de Juan-Sanz

📢Convocatoria 2026 de 10 plazas para la @academiajoven.bsky.social ➡️Plazo de inscripción abierto hasta el 28 de febrero (improrrogable) Más información en: academiajoven.es 👉[email protected]

Exciting new tool for the study of mitochondrial metabolism! Thank you @jdejuan-sanz.bsky.social for sharing your plasmids.

The new Cajal Center is opening 8 CSIC permanent research positions (CT, IC & PF levels) via national competitive exams. We welcome candidates eager to shape an ambitious 🧠 research hub in Spain. 🔗 sede.csic.gob.es/tramites/con... 📣 #Neuroscience #CNC #CSIC #ScienceJobs 👇🏼

Y tú ¿Qué quieres ser de mayor? La @academiajoven.bsky.social lucha para que ninguna niña deje de soñar, imaginar, de innovar, Y ESTIMULA la curiosidad CIENTÍFICA y el interés por aprender de las niñas y las jóvenes. ¡Que todas las MUJERES puedan SEGUIR SUS VOCACIONES CIENTÍFICAS!

Can we make brains “smarter”? By boosting mitochondrial metabolism in neurons of memory circuits, we improved memory in flies and mice. Thrilled to see this work out - congrats to @amrapalianjali.bsky.social for spectacular work, and to all lab members for invaluable contributions!

And forgot to say we made all tools available at @addgene.bsky.social at www.addgene.org/browse/artic... including our new low affinity MitoGCaMP for in vivo fly measurements of mitochondrial Ca2+!

And fun to ready the commentary by the Misgeld lab - thanks for highlighting our work! www.nature.com/articles/s42...

3mo

5mo

4mo

3mo

4mo

Video

Nature Metabolism, Published online: 11 February 2026; doi:10.1038/s42255-025-01448-xCalcium entry into mitochondria couples neuronal activity to energy supply, but whether boosting this drive can enhance brain function has remained unclear. Vishwanath et al. now demonstrate that tuning mitochondrial calcium extrusion enhances ATP production and improves cognitive performance in flies and mice, paving the way for a new paradigm of systems neurometabolism.

dlvr.it

Fuelling the brain with calcium

Mitochondrial Ca2+ efflux controls neuronal metabolism and long-term memory across species

Nature Metabolism, Published online: 11 February 2026; doi:10.1038/s42255-026-01451-wBoosting mitochondrial metabolism in neurons in central memory circuits by enhancing Ca2+ retention in the mitochondrial matrix is shown to improve long-term memory formation in flies and mice.

dlvr.it

Academia Joven de España

Addgene

Liset M. de la Prida

Jaime de Juan-Sanz

sede.csic.gob.es

Nature Metabolism

Jaime de Juan-Sanz

Nature Metabolism

www.addgene.org

Calcium entry into mitochondria couples neuronal activity to energy supply, but whether boosting this drive can enhance brain function has remained unclear. Vishwanath et al. now demonstrate that tuni...

Addgene: Mitochondrial Ca(2+) efflux controls neuronal metabolism and long-term memory across species.

Fuelling the brain with calcium - Nature Metabolism

www.nature.com

And forgot to say we made all tools available at @addgene.bsky.social at www.addgene.org/browse/artic... including our new low affinity MitoGCaMP for in vivo fly measurements of mitochondrial Ca2+!

3mo

4mo

COME AND JOIN US‼️ ** TENURED SCIENTIFIC POSITIONS OPENED** • Brain recovery & neuropathology • Synaptic & computational mechanisms • AI & computational neuroscience • Bioinformatics / Data Science / AI in Biomedicine 📅 Apply by Jan 30, 2026 👉https://shorturl.at/vXCEW [BOE]

4mo