And fun to ready the commentary by the Misgeld lab - thanks for highlighting our work! www.nature.com/articles/s42...
Calcium entry into mitochondria couples neuronal activity to energy supply, but whether boosting this drive can enhance brain function has remained unclear. Vishwanath et al. now demonstrate that tuni...
Can we make brains “smarter”? By boosting mitochondrial metabolism in neurons of memory circuits, we improved memory in flies and mice. Thrilled to see this work out - congrats to @amrapalianjali.bsky.social for spectacular work, and to all lab members for invaluable contributions!
Jaime de Juan-Sanz
dlvr.it
Nature Metabolism, Published online: 11 February 2026; doi:10.1038/s42255-026-01451-wBoosting mitochondrial metabolism in neurons in central memory circuits by enhancing Ca2+ retention in the mitochondrial matrix is shown to improve long-term memory formation in flies and mice.