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Neuroscientist at the Paris Brain Institute / www.dejuansanzlab.org / ERC / FENS-Kavli Scholar / Young Academy of Spain / CNRS
Jaime de Juan-Sanz









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And forgot to say we made all tools available at @addgene.bsky.social at www.addgene.org/browse/artic... including our new low affinity MitoGCaMP for in vivo fly measurements of mitochondrial Ca2+!
3mo
Can we make brains “smarter”? By boosting mitochondrial metabolism in neurons of memory circuits, we improved memory in flies and mice. Thrilled to see this work out - congrats to @amrapalianjali.bsky.social for spectacular work, and to all lab members for invaluable contributions!
Can we make brains “smarter”? By boosting mitochondrial metabolism in neurons of memory circuits, we improved memory in flies and mice. Thrilled to see this work out - congrats to @amrapalianjali.bsky.social for spectacular work, and to all lab members for invaluable contributions!
4mo
4mo
And fun to ready the commentary by the Misgeld lab - thanks for highlighting our work! www.nature.com/articles/s42...
Jaime de Juan-Sanz
Addgene: Mitochondrial Ca(2+) efflux controls neuronal metabolism and long-term memory across species.
www.addgene.org
4mo
Jaime de Juan-Sanz
Jaime de Juan-Sanz
Exciting new tool for the study of mitochondrial metabolism! Thank you @jdejuan-sanz.bsky.social for sharing your plasmids.
Can we make brains “smarter”? By boosting mitochondrial metabolism in neurons of memory circuits, we improved memory in flies and mice. Thrilled to see this work out - congrats to @amrapalianjali.bsky.social for spectacular work, and to all lab members for invaluable contributions!
4mo
3mo
Jaime de Juan-Sanz
📢Convocatoria 2026 de 10 plazas para la @academiajoven.bsky.social ➡️Plazo de inscripción abierto hasta el 28 de febrero (improrrogable) Más información en: academiajoven.es 👉[email protected]
Calcium entry into mitochondria couples neuronal activity to energy supply, but whether boosting this drive can enhance brain function has remained unclear. Vishwanath et al. now demonstrate that tuni...
www.nature.com
Fuelling the brain with calcium - Nature Metabolism
4mo
3mo
Nature Metabolism, Published online: 11 February 2026; doi:10.1038/s42255-025-01448-xCalcium entry into mitochondria couples neuronal activity to energy supply, but whether boosting this drive can enhance brain function has remained unclear. Vishwanath et al. now demonstrate that tuning mitochondrial calcium extrusion enhances ATP production and improves cognitive performance in flies and mice, paving the way for a new paradigm of systems neurometabolism.
dlvr.it
Fuelling the brain with calcium
Can we make brains “smarter”? By boosting mitochondrial metabolism in neurons of memory circuits, we improved memory in flies and mice. Thrilled to see this work out - congrats to @amrapalianjali.bsky.social for spectacular work, and to all lab members for invaluable contributions!
Jaime de Juan-Sanz
4mo
4mo
4mo
4mo
And forgot to say we made all tools available at @addgene.bsky.social at www.addgene.org/browse/artic... including our new low affinity MitoGCaMP for in vivo fly measurements of mitochondrial Ca2+!
Nature Metabolism
Y tú ¿Qué quieres ser de mayor? La @academiajoven.bsky.social lucha para que ninguna niña deje de soñar, imaginar, de innovar, Y ESTIMULA la curiosidad CIENTÍFICA y el interés por aprender de las niñas y las jóvenes. ¡Que todas las MUJERES puedan SEGUIR SUS VOCACIONES CIENTÍFICAS!
Nature Metabolism, Published online: 11 February 2026; doi:10.1038/s42255-026-01451-wBoosting mitochondrial metabolism in neurons in central memory circuits by enhancing Ca2+ retention in the mitochondrial matrix is shown to improve long-term memory formation in flies and mice.
dlvr.it
Nature Metabolism, Published online: 11 February 2026; doi:10.1038/s42255-026-01451-wBoosting mitochondrial metabolism in neurons in central memory circuits by enhancing Ca2+ retention in the mitochondrial matrix is shown to improve long-term memory formation in flies and mice.
Mitochondrial Ca2+ efflux controls neuronal metabolism and long-term memory across species
Mitochondrial Ca2+ efflux controls neuronal metabolism and long-term memory across species
dlvr.it
dlvr.it
Nature Metabolism, Published online: 11 February 2026; doi:10.1038/s42255-026-01451-wBoosting mitochondrial metabolism in neurons in central memory circuits by enhancing Ca2+ retention in the mitochondrial matrix is shown to improve long-term memory formation in flies and mice.
Mitochondrial Ca2+ efflux controls neuronal metabolism and long-term memory across species
3mo
4mo
Nature Metabolism
Nature Metabolism
4mo
Nature Metabolism
Jaime de Juan-Sanz
Addgene
Video
The new Cajal Center is opening 8 CSIC permanent research positions (CT, IC & PF levels) via national competitive exams. We welcome candidates eager to shape an ambitious 🧠 research hub in Spain. 🔗 sede.csic.gob.es/tramites/con... 📣 #Neuroscience #CNC #CSIC #ScienceJobs 👇🏼
Jaime de Juan-Sanz
5mo
Nature Metabolism, Published online: 11 February 2026; doi:10.1038/s42255-026-01451-wBoosting mitochondrial metabolism in neurons in central memory circuits by enhancing Ca2+ retention in the mitochondrial matrix is shown to improve long-term memory formation in flies and mice.
dlvr.it
Mitochondrial Ca2+ efflux controls neuronal metabolism and long-term memory across species
www.addgene.org
Addgene: Mitochondrial Ca(2+) efflux controls neuronal metabolism and long-term memory across species.
Nature Metabolism
4mo
Can we make brains “smarter”? By boosting mitochondrial metabolism in neurons of memory circuits, we improved memory in flies and mice. Thrilled to see this work out - congrats to @amrapalianjali.bsky.social for spectacular work, and to all lab members for invaluable contributions!
4mo
Nature Metabolism, Published online: 11 February 2026; doi:10.1038/s42255-026-01451-wBoosting mitochondrial metabolism in neurons in central memory circuits by enhancing Ca2+ retention in the mitochondrial matrix is shown to improve long-term memory formation in flies and mice.
dlvr.it
Mitochondrial Ca2+ efflux controls neuronal metabolism and long-term memory across species
sede.csic.gob.es
Nature Metabolism
Jaime de Juan-Sanz
4mo
Nature Metabolism, Published online: 11 February 2026; doi:10.1038/s42255-026-01451-wBoosting mitochondrial metabolism in neurons in central memory circuits by enhancing Ca2+ retention in the mitochondrial matrix is shown to improve long-term memory formation in flies and mice.
dlvr.it
Mitochondrial Ca2+ efflux controls neuronal metabolism and long-term memory across species
Nature Metabolism
Liset M. de la Prida
Academia Joven de España
Academia Joven de España
COME AND JOIN US‼️ ** TENURED SCIENTIFIC POSITIONS OPENED** • Brain recovery & neuropathology • Synaptic & computational mechanisms • AI & computational neuroscience • Bioinformatics / Data Science / AI in Biomedicine 📅 Apply by Jan 30, 2026 👉https://shorturl.at/vXCEW [BOE]
5mo