10 days left – Sign up now for the EMBO Workshop "#RNA metabolism: Perspective from physiology to brain disorder" in Darjeeling, #India, 25–28 Oct 2026.
Deadline: 15 May
https://meetings.embo.org/event/26-rna-metabolism
#EMBOrnaMetabolism #RNAsky #LifeSciences #research #conference #EMBOevents 🧪
On this day, in 1961, two articles appeared in Nature announcing the isolation of messenger RNA (mRNA)
www.cell.com/current-biol...
Happy to share our latest paper: www.nature.com/articles/s41...
Great collaboration with @ifremer.bsky.social, @cbitoulouse.bsky.social & @pasteur.fr.
Studying stress in P. abyssi with near-native, minimally purified ribosomes, we identified HibA, a new hibernation factor widespread in Archaea.
How does a scanning ribosome decide where to start protein synthesis?
In our new bioRxiv preprint, we identify an extended translation initiation sequence, the eTIS, an ~80-nt region around the start codon that shapes initiation efficiency:
www.biorxiv.org/content/10.6...
#Ribosome #CryoEM #mRNA
New paper from the lab. "Cap-adjacent 2′-O-ribose methylation of RNA in C. elegans is required for postembryonic growth and germline development in the presence of the decapping exonuclease EOL-1". This thread explains the background to the paper and our key findings. doi.org/10.1093/nar/... 1/15
📻️ Again, live on air (well, pre-recorded) at BBC Radio!
Together with Dr Nick Gaunt, I will be talking about our Keep it Science podcast.
This season, we put a spotlight on Rare Disease.
> www.bbc.co.uk/programmes/p...
Big thanks to our wonderful guests!
#podcast #rareDisease #autoimmune
Ribosome collisions trigger tmRNA-mediated rescue through mRNA disengagement www.biorxiv.org/content/10.6... 🦠
Excited to share our work uncovering SNOR, a ribosome-associated factor that promotes translation restart after dormancy published in Nature!! This was, as usual, a wonderful collaborative effort between our group and the Mattei Lab @simonemattei.bsky.social @embl.org www.nature.com/articles/s41...
The hidden rules behind mRNA transport.
A collaborative study between @simonbullock11.bsky.social & @carter-lab.bsky.social’s groups has found a structural code that explains how cells selectively transport mRNAs.
Read more: mrclmb.ac.uk/news-events/...
#LMBNews @cellbiol-mrclmb.bsky.social 🧪
Cobb looks back at the complicated series events that led to the discovery of messenger
RNA, highlighting the often difficult problem of attributing credit for scientific
advances.
"Pancreatic cancer mRNA vaccine shows lasting results in an early trial: Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later."
niels-fischer.bsky.social
Jonathan Pettitt
Happy to share our preprint!
Using massively parallel reporter assays, single-molecule imaging, deep learning and cryo-EM, we decode the sequence requirements for translation initiation and describe the “extended translation initiation sequence” (eTIS) that modulates start codon recognition.
🧵👇
