New paper from the lab. "Cap-adjacent 2′-O-ribose methylation of RNA in C. elegans is required for postembryonic growth and germline development in the presence of the decapping exonuclease EOL-1". This thread explains the background to the paper and our key findings. doi.org/10.1093/nar/... 1/15
Abstract. Cap-adjacent 2′-O-ribose methylation (cOMe) of the first two transcribed nucleotides of RNA polymerase II transcripts is a conserved feature in m