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10 days left – Sign up now for the EMBO Workshop "#RNA metabolism: Perspective from physiology to brain disorder" in Darjeeling, #India, 25–28 Oct 2026. Deadline: 15 May https://meetings.embo.org/event/26-rna-metabolism #EMBOrnaMetabolism #RNAsky #LifeSciences #research #conference #EMBOevents 🧪
Ribosome collisions trigger tmRNA-mediated rescue through mRNA disengagement www.biorxiv.org/content/10.6... 🦠
📻️ Again, live on air (well, pre-recorded) at BBC Radio! Together with Dr Nick Gaunt, I will be talking about our Keep it Science podcast. This season, we put a spotlight on Rare Disease. > www.bbc.co.uk/programmes/p... Big thanks to our wonderful guests! #podcast #rareDisease #autoimmune
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Happy to share our latest paper: www.nature.com/articles/s41... Great collaboration with @ifremer.bsky.social, @cbitoulouse.bsky.social & @pasteur.fr. Studying stress in P. abyssi with near-native, minimally purified ribosomes, we identified HibA, a new hibernation factor widespread in Archaea.
New paper from the lab. "Cap-adjacent 2′-O-ribose methylation of RNA in C. elegans is required for postembryonic growth and germline development in the presence of the decapping exonuclease EOL-1". This thread explains the background to the paper and our key findings. doi.org/10.1093/nar/... 1/15
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Excited to share our work uncovering SNOR, a ribosome-associated factor that promotes translation restart after dormancy published in Nature!! This was, as usual, a wonderful collaborative effort between our group and the Mattei Lab @simonemattei.bsky.social @embl.org www.nature.com/articles/s41...
"Pancreatic cancer mRNA vaccine shows lasting results in an early trial: Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later."
www.biorxiv.org
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Video
Abstract. Cap-adjacent 2′-O-ribose methylation (cOMe) of the first two transcribed nucleotides of RNA polymerase II transcripts is a conserved feature in m
Cap-adjacent 2′-O-ribose methylation of RNA in C. elegans is required for postembryonic growth and germline development in the presence of the decapping exonuclease EOL-1
doi.org
How does a scanning ribosome decide where to start protein synthesis? In our new bioRxiv preprint, we identify an extended translation initiation sequence, the eTIS, an ~80-nt region around the start codon that shapes initiation efficiency: www.biorxiv.org/content/10.6... #Ribosome #CryoEM #mRNA
On this day, in 1961, two articles appeared in Nature announcing the isolation of messenger RNA (mRNA) www.cell.com/current-biol...
EMBO
Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later.
www.nbcnews.com
Pancreatic cancer mRNA vaccine shows lasting results in an early trial
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Clément Madru
www.cell.com
Cobb looks back at the complicated series events that led to the discovery of messenger RNA, highlighting the often difficult problem of attributing credit for scientific advances.
Who discovered messenger RNA?
Jonathan Pettitt
Zeynep Baharoglu
Elisabeth Kugler
The hidden rules behind mRNA transport. A collaborative study between @simonbullock11.bsky.social & @carter-lab.bsky.social’s groups has found a structural code that explains how cells selectively transport mRNAs. Read more: mrclmb.ac.uk/news-events/... #LMBNews @cellbiol-mrclmb.bsky.social 🧪
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niels-fischer.bsky.social
Ahmad Jomaa
Ignacio Gallup-Diaz
Alejandro Montenegro