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Peggy Goodell
The Goodell Lab. Hematopoietic stem cells, epigenetics, DNA methylation. Houston Texas. Posts are my own.
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Original work here ⬇️, led by the inimitable Lorenzo Brunetti and Michael Gundry. This work became foundational in the field.
Happy to share our review at Cell Stem Cell as part of their Hallmarks series. As always, a pleasure to work with friends and colleagues Anne Brunet (@brunetlab.bsky.social) and Peggy Goodell(@goodell-lab.bsky.social). Hallmarks of stem cell aging: Cell Stem Cell www.cell.com/cell-stem-ce...
6mo
Now: NPM1c becomes a nestling contemplating potential destinies—(1) majesty of wild-type NPM1’s eagle-like order (2) a menacing hawk that shatters the nucleus as it sparks C-body formation and unleashes HOX programs - subverting life-giving differentiation to life-taking self-perpetuation
11mo