New work from Sashi Weerawarana on how TFAM compacts mitochondrial DNA 🧬
TFAM oligomerizes on DNA to form compact, homogeneous higher-order complexes (see beautiful mass photometry data below), that still retain dynamic behavior. Congratulations Sashi and Wei. www.biorxiv.org/content/10.6...
the deadline is rapidly approaching:
Group leader Miguel Leung has been awarded the Young Scientists Award 2026 from @heinekenprizes.bsky.social . With his group, he investigates the 3D structure of protein complexes, tiny machines at work inside each of our cells. Congratulations, Miguel! Read more: www.hubrecht.eu/heineken-you...
Looking forward to starting a new project with @bakkerslab.bsky.social to learn how chromatin changes to allow regeneration in the heart.
Do not miss this HIRA Hulk structure! 🤓👏👏
But wait! There’s more! So you thought you knew nucleosome structure? Think again! @vram142.bsky.social @gladstoneinst.bsky.social and @genophoria.bsky.social @arcinstitute.org show that there is plenty of distortion largely due to TFs butting in www.nature.com/articles/s41...
We are looking for a PhD student to study chromatin changes related to heart regeneration, in collaboration with @bakkerslab.bsky.social . Please share and apply!
www.hubrecht.eu/nl/vacature/...
Our work on chromatin evolution in brown algae is now published in @natecoevo.nature.com! We show that developmentally complex brown algae evolved without epigenetic silencing pathways long thought universal, underscoring why non-model lineages are important to study. www.nature.com/articles/s41...
Here is the full 2026/27 program of @genomeiinetwork.bsky.social virtual seminars, chaired by myself and @dimiccolab.bsky.social. Scan the QR code to receive alerts and automated calendar. Don't miss a bunch of exciting talks from established and emerging leaders in genome integrity world-wide!
The newly established NeCEN Utrecht is looking for a #cryoEM scientist!
www.uu.nl/en/organisat...
Work with a new Krios 5 + pFIB and support cutting-edge life science research.
📍 Utrecht | 🗓 Apply by 30 April
Please share with your network!
We are looking for PhD student in the group of Dr. Francesca Mattiroli at the Hubrecht Institute. The successful candidate will work in a collaborative project between the Mattiroli lab and the lab of...
www.hubrecht.eu
www.nature.com
An analytical pipeline called Iteratively Defined Lengths of Inaccessibility (IDLI) maps the genome-wide occupancy of a range of nucleosome types and shows that most nucleosomes exhibit programmed ‘di...
Out today - structure of the human HIRA histone chaperone complex bound to nucleosomes. Ever wondered how nucleosomes are assembled in the wake of transcription? It takes a 'hulk of a protein complex'. Work by the amazing Wei Tian weetian558.bsky.social. www.biorxiv.org/content/10.6... 🧵
Lopes_Lab
Francesca Mattiroli
Francesca Mattiroli
Francesca Mattiroli
Michael Borg
Benoit Bruneau
Karolin Luger
Congratulations! Jeroen den Hertog, @bakkerslab.bsky.social , @fmattiroli.bsky.social and Eva van Rooij received ZonMw Open competition grants to study RASopathies and heart regeneration. Read more here: www.hubrecht.eu/zonmw-grants...
Daniel Hurdiss
Hubrecht Institute
We;re hiring Junior Group Leaders! 🔬✨
We’re looking for researchers in immunology, chemical biology, AI in biology, or protein design to launch their own independent groups in our collaborative, international environment.
www.nki.nl/news-events/...
