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Congratulations Thi Nguyen, @konjikusicmia.bsky.social, Lorenzo del Castillo and Roshank Irannejad on this new paper! I'm proud of you all. Thank you, Dagmar Wachten, for editing. Everyone else, please send thoughts, comments, critiques and questions: plos.io/4v7vdnp
18h
Hedgehog signaling in vertebrates is transduced by the transmembrane protein Smoothened (SMO) on the primary cilium, but the underlying mechanisms remain unclear. This study shows that SMO and ciliary...
plos.io
Smoothened and ciliary GPCRs regulate ciliary protein kinase A activity involved in Hedgehog signal transduction
Jeremy Reiter
Vertebrate #Hedgehog signaling is transduced by transmembrane protein Smoothened (SMO) on the primary #cilium, but what is its mechanism? @reitergroup.bsky.social &co show that SMO & ciliary GPCRs regulate ciliary PKA activity to activate the Hedgehog pathway @plosbiology.org 🧪 plos.io/4v7vdnp
The jerseys also say "Ceci n'est pas un maillot" ("This is not a jersey") on the back. Perfect detail.
19h
4d
Emoticons: E9.5 mouse embryo sections through otocyst, hindbrain and pharyngeal endoderm resemble eyes, nose, and smile of an emoticon. 📸 Image credit: Ankita Thawani (Baylor College of Medicine) #FluorescenceFriday #Embryology #DevelopmentalBiology #Microscopy #ScienceArt✨ 🧬
6d
Stay tuned for Rush madness in a few hours!
Doug Mack
PLOS Biology
11h
Netflix has unveiled an October 23 release date and poster for Part 4 of its French-language crime drama hit Lupin starring Omar Sy as gentleman thief Assane Diop.
3d
does the eagle know its role in Prometheus's punishment or is it just showing up every day like "holy shit, free liver AGAIN??"
1d
Society for Developmental Biology
I have a moral obligation to repost this every time raw milk is in the news.
19h