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P.S.: If you are excited about how mechanics regulates cellular physiology, please reach out! My lab is actively looking for curious and creative students/postdocs to join our growing team and discover exciting new biology with us. cri.utsw.edu/faculty/henr...
5d
Children’s Medical Center Research Institute at UT Southwestern (CRI) is a joint venture of UT Southwestern Medical Center and Children’s ...
cri.utsw.edu
Henry De Belly - Children's Medical Center Research Institute (CRI) | Dallas Texas
Congratulations, @konjikusicmia.bsky.social. It makes my heart well up to have this cohort named in memory of Zara, an extraordinary scientist.
7d
Henry De Belly
The ciliary PKA activity sensor is sensitive and easy to use. It's useful for assessing Hedgehog pathway state and ciliary GPCR output. Let me know if you want to try it!
4d
FASEB Cilia and Centrosomes. Abstract submission deadline is TODAY! Come share your exciting science with the community! events.faseb.org/event/cilia-...
Jeremy Reiter
8d
Vertebrate #Hedgehog signaling is transduced by transmembrane protein Smoothened (SMO) on the primary #cilium, but what is its mechanism? @reitergroup.bsky.social &co show that SMO & ciliary GPCRs regulate ciliary PKA activity to activate the Hedgehog pathway @plosbiology.org πŸ§ͺ plos.io/4v7vdnp
Congratulations Thi Nguyen, @konjikusicmia.bsky.social, Lorenzo del Castillo and Roshank Irannejad on this new paper! I'm proud of you all. Thank you, Dagmar Wachten, for editing. Everyone else, please send thoughts, comments, critiques and questions: plos.io/4v7vdnp
5d
4d
Important new work from Chia-Hsiang Chang, @nachury.bsky.social and colleagues identifying the composition of neuronal cilia in an unbiased way. Lots of surprises herein: www.science.org/doi/10.1126/...
10d
Jeremy Reiter
Jeremy Reiter
Hedgehog signaling in vertebrates is transduced by the transmembrane protein Smoothened (SMO) on the primary cilium, but the underlying mechanisms remain unclear. This study shows that SMO and ciliary...
In situ proteomics and expansion microscopy reveal nanoscale organization of postsynaptic proteins on neuronal cilia.
Jeremy Reiter
www.science.org
Smoothened and ciliary GPCRs regulate ciliary protein kinase A activity involved in Hedgehog signal transduction
In situ proteomics unveils specialized domains for extrasynaptic signaling on neuronal cilia
plos.io
Jeremy Reiter
We are thrilled to announce the 2026 Zara Weinberg Leading Edge Fellows! 40 remarkable postdocs pursuing transformative research in biological/biomedical sciences. This is the 7th Leading Edge cohort and we are so excited to welcome them! www.leadingedgesymposium.org/fellows/
Vertebrate #Hedgehog signaling is transduced by transmembrane protein Smoothened (SMO) on the primary #cilium, but what is its mechanism? @reitergroup.bsky.social &co show that SMO & ciliary GPCRs regulate ciliary PKA activity to activate the Hedgehog pathway @plosbiology.org πŸ§ͺ plos.io/4v7vdnp
5d
7d
PLOS Biology
PLOS Biology
What if damaged human kidneys could one day repair themselves? At MDI Bio Lab, Iain Drummond, Ph.D., and his team have identified inflammatory signaling pathways in #zebrafish capable of triggering the production of new, functional nephrons without injuring the kidney itself. πŸ§ͺ 🐟🎸 #NephSky #RenalSky
8d
mdibl.org
How to Repair a Kidney Without Making Things Worse
Leading Edge Fellows Program
MDI Biological Laboratory