Cryo-EM: the revolution continues doi.org/10.1107/S205...
The next #CryoEM Current Practices Webinar speaker will be Mark Herzik from UCSD speaking on "Old tools, new tricks: engineering better cryoEM sample preparation workflows through design and chemistry" 6/25/2026 at 12 PM ET / 9AM PT
Register here :
us02web.zoom.us/webinar/regi...
Striking improvement with the laser phase plate to boost contrast, and in exactly the range that's needed for modelling the details of protein structures.
Still lots of headroom in Cryo-EM.
www.science.org/doi/10.1126/...
#biophysics
Beyond excited about this manuscript in collaboration with Aaron Schmidt's lab! They isolated #antibodies from wild-caught Egyptian rousette #bats targeting bat-borne H9N2 #influenza and Bruno Bonnettaz in our lab determined their complex structures by #cryoEM!
www.biorxiv.org/content/10.6...
The increasing democratization and implementation of electron cryo-microscopy appears poised to drive a new revolution in digital structural biology.
In mammals, antibodies are central to antiviral defense, but they can also impose selective pressure that drives viral evolution. The interplay between viral antigenic variation and host antibody dive...
Today my laboratory is thrilled to announce a major breakthrough in the fight against the common cold and other diseases like hand,foot, and mouth disease acute flaccid myelitis caused by picornaviruses. We present the first structure of picornaviral 2C, bound to ssRNA (1/n)
Atomic resolution cryo-EM at 200 keV pubmed.ncbi.nlm.nih.gov/42268577/ #cryoEM
