For those interested in studying cell-cell communication, check out our latest methodological work in AJHG where we discuss more powerful and practical techniques for this task. Project was joint effort with @yjingj.bsky.social and led by our incredible trainee Dr. Qile Dai (now at Lilly)
Multiple Postdoc Positions available in Epidemiology, Biostatistics, or Statistical Genetics (deadline April 15)
Join an International team at the Pioneer Centre for SMARTbiomed, Aarhus, Denmark!
#Postdoc #Epidemiology #StatisticalGenetics #Biostatistics
👉 international.au.dk/about/profil...
Our new AJHG paper is online. We develop a new TWAS tool that uses local-ancestry information to improve power of gene mapping in admixed samples. Lead author Taylor Head (now at MD Anderson) did a phenomenal job spearheading this work!
🧬Online now!
📄Identifying condition-related cell-cell communication events using supervised tensor analysis
🧑🤝🧑 @epsteinstatgen.bsky.social @yjingj.bsky.social & Dai
🖥️ github.com/daiqile96/ST...
Happy Chrismukkah to all the delightful half-half situations (like me)
Cell-cell communication (CCC) events coordinate physiological functions in multicellular
organisms and are important for exploring biological processes and disease mechanisms.
We introduce STACCato, a...
🧬Online now!
📄Identifying condition-related cell-cell communication events using supervised tensor analysis
🧑🤝🧑 @epsteinstatgen.bsky.social @yjingj.bsky.social & Dai
🖥️ github.com/daiqile96/ST...
Michael Epstein
The American Journal of Human Genetics
RIP, Prince of Darkness. Arguably in the Top 5 of most influential artists of my lifetime
🚨New method!
📄CADET: Enhanced transcriptome-wide association analyses in admixed samples using eQTL summary data
🧑🤝🧑 @epsteinstatgen.bsky.social @yjingj.bsky.social & co
www.cell.com
Cell-cell communication (CCC) events coordinate physiological functions in multicellular
organisms and are important for exploring biological processes and disease mechanisms.
We introduce STACCato, a...
I'm hiring a computational biologist interested in complex trait genetics using deep learning approaches. Reach out to me, if interested.
Incredible GRC Genetics and Genomics conference line-up this year in Portland, Maine (www.grc.org/human-geneti...). With conference-maxxing sessions that run to 9:30pm!
Submission deadline is June 8th, conference July 6-11th.
CADET is a transcriptome-wide association test for admixed cohorts that leverages
local ancestry information to improve detection of trait-influencing genes. CADET
outperformed existing methods using ...
www.cell.com
Michael Epstein
Happy to see this out w/ @epsteinstatgen.bsky.social and @davecutler.bsky.social (paper: doi.org/10.1093/bioi...)! We tackled the problem of identifying dysregulated pathways (i.e. differentially co-expressed) in gene expression studies. We show that differential co-expression arises ...
The American Journal of Human Genetics
Excited to see our (w/ @chr1sw.bsky.social) work published in @natcomputsci.nature.com! We developed a new framework, surrogate functional false discovery rate (sffdr), that integrates summary statistics of related traits to improve power in GWASs.
Paper: www.nature.com/articles/s43...
I truly thought this man was going to live forever, somehow. RIP, Ozzy, you were metal incarnate for me. news.sky.com/story/ozzy-o...
This study introduces a cost-effective strategy called surrogate functional false discovery rates to increase power in genome-wide association studies by leveraging genetic correlations (or pleiotropy...
