Excited to see our (w/ @chr1sw.bsky.social) work published in @natcomputsci.nature.com! We developed a new framework, surrogate functional false discovery rate (sffdr), that integrates summary statistics of related traits to improve power in GWASs.
Paper: www.nature.com/articles/s43...
Our new AJHG paper is online. We develop a new TWAS tool that uses local-ancestry information to improve power of gene mapping in admixed samples. Lead author Taylor Head (now at MD Anderson) did a phenomenal job spearheading this work!
Multiple Postdoc Positions available in Epidemiology, Biostatistics, or Statistical Genetics (deadline April 15)
Join an International team at the Pioneer Centre for SMARTbiomed, Aarhus, Denmark!
#Postdoc #Epidemiology #StatisticalGenetics #Biostatistics
👉 international.au.dk/about/profil...
Happy to see this out w/ @epsteinstatgen.bsky.social and @davecutler.bsky.social (paper: doi.org/10.1093/bioi...)! We tackled the problem of identifying dysregulated pathways (i.e. differentially co-expressed) in gene expression studies. We show that differential co-expression arises ...
I'm hiring a computational biologist interested in complex trait genetics using deep learning approaches. Reach out to me, if interested.
RIP, Prince of Darkness. Arguably in the Top 5 of most influential artists of my lifetime
Incredible GRC Genetics and Genomics conference line-up this year in Portland, Maine (www.grc.org/human-geneti...). With conference-maxxing sessions that run to 9:30pm!
Submission deadline is June 8th, conference July 6-11th.
Happy Chrismukkah to all the delightful half-half situations (like me)
www.nature.com
This study introduces a cost-effective strategy called surrogate functional false discovery rates to increase power in genome-wide association studies by leveraging genetic correlations (or pleiotropy...
I truly thought this man was going to live forever, somehow. RIP, Ozzy, you were metal incarnate for me. news.sky.com/story/ozzy-o...
🚨New method!
📄CADET: Enhanced transcriptome-wide association analyses in admixed samples using eQTL summary data
🧑🤝🧑 @epsteinstatgen.bsky.social @yjingj.bsky.social & co
The heavy metal star reunited with his Black Sabbath bandmates on stage at Villa Park earlier in July.
news.sky.com
www.cell.com
CADET is a transcriptome-wide association test for admixed cohorts that leverages
local ancestry information to improve detection of trait-influencing genes. CADET
outperformed existing methods using ...
🧬Online now!
📄Identifying condition-related cell-cell communication events using supervised tensor analysis
🧑🤝🧑 @epsteinstatgen.bsky.social @yjingj.bsky.social & Dai
🖥️ github.com/daiqile96/ST...
The American Journal of Human Genetics
Cell-cell communication (CCC) events coordinate physiological functions in multicellular
organisms and are important for exploring biological processes and disease mechanisms.
We introduce STACCato, a...
For those interested in studying cell-cell communication, check out our latest methodological work in AJHG where we discuss more powerful and practical techniques for this task. Project was joint effort with @yjingj.bsky.social and led by our incredible trainee Dr. Qile Dai (now at Lilly)
🧬Online now!
📄Identifying condition-related cell-cell communication events using supervised tensor analysis
🧑🤝🧑 @epsteinstatgen.bsky.social @yjingj.bsky.social & Dai
🖥️ github.com/daiqile96/ST...
Michael Epstein
Michael Epstein
Michael Epstein
Cell-cell communication (CCC) events coordinate physiological functions in multicellular
organisms and are important for exploring biological processes and disease mechanisms.
We introduce STACCato, a...
