Excited to see our (w/ @chr1sw.bsky.social) work published in @natcomputsci.nature.com! We developed a new framework, surrogate functional false discovery rate (sffdr), that integrates summary statistics of related traits to improve power in GWASs.
Paper: www.nature.com/articles/s43...
This study introduces a cost-effective strategy called surrogate functional false discovery rates to increase power in genome-wide association studies by leveraging genetic correlations (or pleiotropy...