Proud to announce our collaboration with @blurtonjoneslab.bsky.social & the Paz lab showing that transplanted human iPSC-derived microglia in a PGRN KO mouse model restores progranulin in microglia and rescues pathology, circuitry, and behavior. Preprint out now: www.biorxiv.org/cgi/content/...
Cell membrane stress upon viral infection induces expression and stabilization of host SMPDL3B, which, in turn, degrades cGAMP to suppress cGAS-STING signaling and promote viral replication @cp-immunity.bsky.social
www.cell.com/immunity/ful...
New article @natneuro.nature.com by @yaleneuro.bsky.social Suzhou Yang & @kavliatyale.bsky.social Postdoc Fellow @zhenlei.bsky.social, highlighting studies by @frattalab.bsky.social Gitler & La Spada labs on the role of TDP-43 on mRNA 3' end in ALS @yalerna.bsky.social www.nature.com/articles/s41...
Single cell isoform profiling by snISOrseq2 reveals broad splicing dysregulation across different cell types in Progranulin-deficient human FTD! Congrats to @hagentilgner.bsky.social & @liganlab.bsky.social labs! Happy to have played a tiny role in this important study.
www.cell.com/cell-reports...
Great opportunity for neuroscience postdocs!
SPiNES was such a great experience. Highly recommend!
Microglial cGAS-STING-TBK1 activation in paraventricular thalamus mediates sleep and emotional disturbances in lupus mice www.sciencedirect.com/science/arti...
Frontotemporal dementia (FTD) is a major cause of early-onset neurodegeneration characterized by progressive behavioral, emotional, and cognitive decline. Progranulin haploinsufficiency, a leading gen...
In amyotrophic lateral sclerosis (ALS), nuclear depletion and cytoplasmic aggregation of the RNA-binding protein TDP-43 cause widespread dysregulation of mRNA splicing. Two recent studies have now rev...
Belchikov et al. conducted a case-control study of splicing in frontotemporal dementia
using long-read sequencing. They identified multiple splicing-dysregulation events,
including cell-type-specific ...
Thank you, Priya! 🥰
Thank you, @sarahnaguib.bsky.social! I'm gonna miss you 🙂
Congratulations, Priyanka! Very exciting!
Gan Lab
Waggoner Lab
Junjie Guo
John Lukens
Sadaf Amin
Sadaf Amin
Sadaf Amin
#MSNseminars APPLICATION DEADLINE EXTENDED ➡️ September 14th! Senior postdocs (at U.S.-based institutes) in all fields of #Neuroscience are encouraged to apply. INCREDIBLE OPPORTUNITY to share your research, visit Mount Sinai & meet w/ faculty/trainees! Scan QR code on poster to 👉APPLY NOW!
are you a PD in the glia (or neuroscience) space? Do you want to come to NYC and give a lecture and meet some amazing faculty here at @nyumedpostdocs.bsky.social?
LAST WEEK TO APPLY to be a SPiNES speaker for our next season.
Details and apply here: med.nyu.edu/departments-...
COME AND WOW US!
Sadaf Amin
Sadaf Amin
Sadaf Amin
ALT: a black and white photo of a crowd of people standing and sitting in chairs .
