Single cell isoform profiling by snISOrseq2 reveals broad splicing dysregulation across different cell types in Progranulin-deficient human FTD! Congrats to @hagentilgner.bsky.social & @liganlab.bsky.social labs! Happy to have played a tiny role in this important study.
www.cell.com/cell-reports...
Belchikov et al. conducted a case-control study of splicing in frontotemporal dementia
using long-read sequencing. They identified multiple splicing-dysregulation events,
including cell-type-specific ...
