Congrats to @clairesimon.bsky.social and @niakanlab.bsky.social! We were happy to contribute to this great project investigating FGF/ERK signalling in human embryogenesis. @georgiaplea.bsky.social
Spread the word! There is a professor position opening at our University @upcite.bsky.social. There are several possible (great) labs to join, but if you are interested in DNA methylation and epigenetics in mammals, don't hesitate to contact me directly!
I didn't think I could admire Azim Surani more than I already did
journals.biologists.com/dev/article/...
Our latest collaboration with the talented Susi @sbantele.bsky.social and Jiri Lukas is out now @science.org ๐คฉ. We reveal the hidden price for DNA repair, with potential implications for genome function, gene therapy and ageing๐
Very excited to share an excellent review from @teresa-urli.bsky.social, published one week before her PhD defense! We did a deep dive into the fascinating biology of the variant Polycomb complex, PRC1.6 (1/5) journals.plos.org/plosgenetics...
journals.biologists.com
In mammals, repression of germline-specific gene expression is essential for preserving somatic cell identity and preventing disease. Germline gene silencing is often dependent on the presence of prom...
journals.plos.org
Professor Azim Surani is the Director of Epigenomics and Germline Imprinting at the Gurdon Institute in Cambridge, UK. He is this year's recipient of both the prestigious Kyoto Prize and the Paul Ehrl...
This will be a great meeting! Don't forget to register!
Delighted to see this out! Human embryos depend on FGF/ERK signalling to specify epiblast versus primitive endoderm cells. Well done Claire Simon and the lab for their contributions! Many thanks to Mary Herbert @josh-brickman.bsky.social @cwhanna.bsky.social labs for brilliant contributions!
#JobOffer
๐ผ Un poste susceptible dโรชtre vacant de Professeur en stabilitรฉ des gรฉnomes devrait sโouvrir pour la rentrรฉe 2026 au sein de lโInstitut Jacques Monod
โก๏ธ Informations concernant ce poste et la procรฉdure de candidature ๐ www.ijm.fr/poste-de-pro...
๐๐ฎ๐ป ๐ฐ๐ฒ๐น๐น๐ ๐ฒ๐๐ฒ๐ฟ ๐๐ฟ๐๐น๐ ๐ฟ๐ฒ๐ฐ๐ผ๐๐ฒ๐ฟ ๐ณ๐ฟ๐ผ๐บ ๐๐ก๐ ๐ฑ๐ฎ๐บ๐ฎ๐ด๐ฒ?Excited to share our new study โRepair of DNA double-strand breaks leaves heritable impairment to genome functionโ, revealing DNA repairโs hidden cost, out now @science.org tinyurl.com/5n6zw3ye. Led by @sbantele.bsky.social and Jiri Lukas.๐งต๐1/n
tinyurl.com
Upon DNA breakage, a genomic locus undergoes alterations in three-dimensional chromatin architecture to facilitate signaling and repair. Although cells possess mechanisms to repair damaged DNA, it is ...
Nature Communications - The authors show human embryo lineage specification in the blastocyst is driven by differential FGF/ERK signaling, which segregates yolk sac-fated hypoblast and embryonic...
We're excited to publish our latest study led by Bryony Leeke @bryonyleeke.bsky.social and Wazeer Varsally, now out in @nature.com ๐พThis study focusses on the epigenome of marsupial embryos ๐ฆ mapping DNA methylation in embryo development to specific embryo events www.nature.com/articles/s41... ๐งต
A study reports on the DNA methylation dynamics during embryogenesis in marsupials, showing that these differ from those occurring during embryogenesis in eutherian mammals.
An insight into advances in the field of placental biology and their importance: www.nature.com/articles/d41...
"why [would] anyone intelligent enough to be a scientist choose to be one [given] the unfavorable risk-to-reward ratio "?
One of the most intelligent people you could meet offers some answers: having ideas, watching them develop, and sharing them journals.biologists.com/jcs/article/...
Lab-made organoids that mimic reproductive tissues could point to treatments for common conditions such as pre-eclampsia and endometriosis.
It is difficult to fathom why anyone intelligent enough to be a scientist would actually choose to be one. Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently...
๐ข Job opportunity: Research Associate in lung epigenetics at Cardiff University with Dr Renata Jurkowska
๐ Deadline: 4 March
๐https://krb-sjobs.brassring.com/TGnewUI/Search/Home/HomeWithPreLoad?partnerid=30011&siteid=5460&PageType=searchResults&SearchType=linkquery&LinkID=6#jobDetails=2266401_5460
Exciting News!
๐ Registration Open! | Loke CTR Annual Meeting 2026 ๐
๐ 16-17 July 2026
๐ St Johnโs College, Cambridge | ๐ป Hybrid conference (in-person & online)
๐ฌ Epigenetics of embryogenesis and placentation
๐ To find out more and to register
www.trophoblast.cam.ac.uk/ctrconferenc...
