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Sir Henry Dale Fellow/Group Leader, Centre for Trophoblast Research, University of Cambridge, interested in trophoblast, epigenetics and developmental biology
Courtney Hanna









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Congrats to @clairesimon.bsky.social and @niakanlab.bsky.social! We were happy to contribute to this great project investigating FGF/ERK signalling in human embryogenesis. @georgiaplea.bsky.social
10mo
"why [would] anyone intelligent enough to be a scientist choose to be one [given] the unfavorable risk-to-reward ratio "? One of the most intelligent people you could meet offers some answers: having ideas, watching them develop, and sharing them journals.biologists.com/jcs/article/...
10mo
This will be a great meeting! Don't forget to register!
We're excited to publish our latest study led by Bryony Leeke @bryonyleeke.bsky.social and Wazeer Varsally, now out in @nature.com 🍾This study focusses on the epigenome of marsupial embryos 🦘 mapping DNA methylation in embryo development to specific embryo events www.nature.com/articles/s41... 🧵
3mo
Courtney Hanna
May 14, 2025
Richard Sever
Courtney Hanna
📢 Job opportunity: Research Associate in lung epigenetics at Cardiff University with Dr Renata Jurkowska 📅 Deadline: 4 March 🔗https://krb-sjobs.brassring.com/TGnewUI/Search/Home/HomeWithPreLoad?partnerid=30011&siteid=5460&PageType=searchResults&SearchType=linkquery&LinkID=6#jobDetails=2266401_5460
An insight into advances in the field of placental biology and their importance: www.nature.com/articles/d41...
I didn't think I could admire Azim Surani more than I already did journals.biologists.com/dev/article/...
Spread the word! There is a professor position opening at our University @upcite.bsky.social. There are several possible (great) labs to join, but if you are interested in DNA methylation and epigenetics in mammals, don't hesitate to contact me directly!
3mo
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7mo
Turner Lab
Very excited to share an excellent review from @teresa-urli.bsky.social, published one week before her PhD defense! We did a deep dive into the fascinating biology of the variant Polycomb complex, PRC1.6 (1/5) journals.plos.org/plosgenetics...
9mo
Naomi McGovern
British Association for Lung Research
Exciting News! 🚀 Registration Open! | Loke CTR Annual Meeting 2026 🎉 📅 16-17 July 2026 📍 St John’s College, Cambridge | 💻 Hybrid conference (in-person & online) 🔬 Epigenetics of embryogenesis and placentation 📌 To find out more and to register www.trophoblast.cam.ac.uk/ctrconferenc...
Maxim Greenberg
Julien Richard Albert
4mo
Maxim Greenberg
Our latest collaboration with the talented Susi @sbantele.bsky.social and Jiri Lukas is out now @science.org 🤩. We reveal the hidden price for DNA repair, with potential implications for genome function, gene therapy and ageing👇
7mo
The Loke Centre for Trophoblast Research
It is difficult to fathom why anyone intelligent enough to be a scientist would actually choose to be one. Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently...
journals.biologists.com
Professor Azim Surani is the Director of Epigenomics and Germline Imprinting at the Gurdon Institute in Cambridge, UK. He is this year's recipient of both the prestigious Kyoto Prize and the Paul Ehrl...
journals.biologists.com
Why would anyone want to be a scientist?
An interview with Azim Surani
The Groth lab
Epigenetic relay: Polycomb-directed DNA methylation in mammalian development
In mammals, repression of germline-specific gene expression is essential for preserving somatic cell identity and preventing disease. Germline gene silencing is often dependent on the presence of prom...
journals.plos.org
A study reports on the DNA methylation dynamics during embryogenesis in marsupials, showing that these differ from those occurring during embryogenesis in eutherian mammals.
www.nature.com
Divergent DNA methylation dynamics in marsupial and eutherian embryos - Nature
𝗖𝗮𝗻 𝗰𝗲𝗹𝗹𝘀 𝗲𝘃𝗲𝗿 𝘁𝗿𝘂𝗹𝘆 𝗿𝗲𝗰𝗼𝘃𝗲𝗿 𝗳𝗿𝗼𝗺 𝗗𝗡𝗔 𝗱𝗮𝗺𝗮𝗴𝗲?Excited to share our new study “Repair of DNA double-strand breaks leaves heritable impairment to genome function”, revealing DNA repair’s hidden cost, out now @science.org tinyurl.com/5n6zw3ye. Led by @sbantele.bsky.social and Jiri Lukas.🧵👇1/n
7mo
Lab-made organoids that mimic reproductive tissues could point to treatments for common conditions such as pre-eclampsia and endometriosis.
The mini placentas and ovaries revealing the basics of women’s health
www.nature.com
Upon DNA breakage, a genomic locus undergoes alterations in three-dimensional chromatin architecture to facilitate signaling and repair. Although cells possess mechanisms to repair damaged DNA, it is ...
tinyurl.com
Repair of DNA double-strand breaks leaves heritable impairment to genome function
Susi Bantele
#JobOffer 💼 Un poste susceptible d’être vacant de Professeur en stabilité des génomes devrait s’ouvrir pour la rentrée 2026 au sein de l’Institut Jacques Monod ➡️ Informations concernant ce poste et la procédure de candidature 🔗 www.ijm.fr/poste-de-pro...
7mo
Delighted to see this out! Human embryos depend on FGF/ERK signalling to specify epiblast versus primitive endoderm cells. Well done Claire Simon and the lab for their contributions! Many thanks to Mary Herbert @josh-brickman.bsky.social @cwhanna.bsky.social labs for brilliant contributions!
10mo
Institut Jacques Monod
Niakan Lab
Nature Communications - The authors show human embryo lineage specification in the blastocyst is driven by differential FGF/ERK signaling, which segregates yolk sac-fated hypoblast and embryonic...
rdcu.be
Suppression of ERK signalling promotes pluripotent epiblast in the human blastocyst