Ultrastructure of dopaminergic varicosities revealed by cryo-correlative light and electron microscopy. New study from Matthew Domenic Lycas (@lycasworks.bsky.social), Simon Erlendsson et al. @ucph.bsky.social:
rupress.org/jcb/article/...
#Neuroscience #Organelles #StructuralBiology #cryoCLEM
This mesmerizing timelapse captures the nonstop motion inside an animal cell. Red/orange streaks are the growing ends of microtubules, tiny “highways” that can rapidly assemble and disassemble to move proteins & other molecules within the cell.
📸: Andy Moore, HHMI’s Janelia Research Campus
My first corresponding author 🔬🎸🦾
rupress.org/jcb/article/...
Ever wonder what the ultrastructure of dopaminergic neuron presynaptic sites looks like? Using cryo-CLEM/ET we observed the wild changes that happen at these sites when the neurons fire or are more quiet.
In the latest @jcb.org
