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My first corresponding author 🔬🎸🦾 rupress.org/jcb/article/... Ever wonder what the ultrastructure of dopaminergic neuron presynaptic sites looks like? Using cryo-CLEM/ET we observed the wild changes that happen at these sites when the neurons fire or are more quiet. In the latest @jcb.org
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Lycas et al. develop a cryo-CLEM workflow to characterize the ultrastructure of dopaminergic varicosities. They resolve in situ structures of TRiC/CCT and
rupress.org
Ultrastructure of dopaminergic varicosities revealed by cryo-correlative light and electron microscopy
Matt Lycas