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My first corresponding author 🔬🎸🦾 rupress.org/jcb/article/... Ever wonder what the ultrastructure of dopaminergic neuron presynaptic sites looks like? Using cryo-CLEM/ET we observed the wild changes that happen at these sites when the neurons fire or are more quiet. In the latest @jcb.org
Got my pictures back
1mo
1mo
rupress.org
Lycas et al. develop a cryo-CLEM workflow to characterize the ultrastructure of dopaminergic varicosities. They resolve in situ structures of TRiC/CCT and
Ultrastructure of dopaminergic varicosities revealed by cryo-correlative light and electron microscopy
Matt Lycas
Matt Lycas
In @jcb.org, @lycasworks.bsky.social, Erlendsson et al. @ucph.bsky.social develop a #cryoCLEM workflow to characterize the ultrastructure of dopaminergic varicosities. rupress.org/jcb/article/... #Neuroscience #Organelles #StructuralBiology #Microscopy
1mo
Home microscope project - high NA Phase contrast with the fun Lowa objective Lomo inverted with the Lomo 1.25 NA water inversion phase contrast Need to add light source and camera and phase annulus
Expansion microscopy rocks
*water immersion