Medical Doctor, Doctoral Student in the Winkler Lab at the German Cancer Research Center, Heidelberg; interested in (brain) metastases and the tumor microenvironment
Nils Hebach
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More details on our main findings in this thread 🧵👇: bsky.app/profile/matt...
Nils Hebach
What if brain metastatic cells do not act alone, but form #networks to help them grow?
In our new #preprint, we show that #brainmetastases form malignant, gap-junction mediated #networks that drive cell cycle progression & neural features through Ca²⁺ signaling.
www.biorxiv.org/content/10.6...
🧵👇
Researchers at the Crick have uncovered how lung tumours can hijack the activity of nearby nerves to weaken the body’s immune response.
This research was led by Ya-Hsuan Ho and Giacomo Bregni, with corresponding author Leanne Li.
www.crick.ac.uk/news/2026-05...
Excited to share our ‘Evolutionary characterization of lung cancer metastasis’ in #TRACERx & #PEACE, published today in @nature.com in collaboration with @charlesswanton.bsky.social @nickymcgranahan.bsky.social @zaccasimo.bsky.social at @ucl.ac.uk & @crick.ac.uk. www.nature.com/articles/s41...
Video
The UK rejoining Erasmus is the best science news for a while! #AcademicSky
www.gov.uk/government/n...
Among patients with previously treated metastatic pancreatic ductal adenocarcinoma, the RAS(ON) inhibitor daraxonrasib led to significantly longer overall survival and progression-free survival than chemotherapy. Full phase 3 RASolute 302 trial results: https://nej.md/4nWaxvM
#ASCO26
Sensory nerve activity disrupts how immune cells are organised within lung tumours, weakening the immune response.
Incredible to see our work out today in Cell: "Plasma signals of lung tumor promotion for molecular cancer prevention."
www.cell.com/cell/fulltex...
Matthia Karreman
DNA-sequencing data from primary tumours and paired metastases from participants in the TRACERx lung study and PEACE autopsy programme are used to analyse the metastatic diversity of advanced non-smal...
Thousands across the UK set to benefit from re-opening of the historic Erasmus+ programme
www.gov.uk
Thrilled to share our new paper out today in @NatureCancer:A single dose of RT makes CAR T cells work against extensive metastatic lung cancer — even when the target antigen is also on normal tissues. (1/14)
nature.com/articles/s43018-026-01167-6
Jamal-Hanjani Lab
Prof Jenny Rohn
A 14-protein plasma signature identifies individuals benefiting from anti-IL-1β-based
lung cancer risk reduction and demonstrates how diverse tumor-promoting factors converge
on the induction of an al...
How does the nervous system influence cancer ... and vice versa?
Now online @cp-cell.bsky.social our newest review on current and emerging topics in Cancer Neuroscience 🧠, and many new exciting directions ahead.
www.sciencedirect.com/science/arti...
Happy #FluorescenceFriday!
Gap junction inhibition disconnects tumour networks in brain metastases and silences Ca²⁺ oscillations that drive proliferation.
More in our recent preprint : www.biorxiv.org/content/10.6...
Our new preprint on calcium signaling in brain metastases is now on bioRxiv!
Thrilled to share the core work of my doctoral thesis in the @winklerlab.bsky.social, together with @nielsolshausen.bsky.social, @matthiakarreman.bsky.social and many more!
Ahmed and colleagues show that, by promoting ‘dressing’ of intact tumor target antigens onto dendritic cells, tumor irradiation enhances chimeric antigen receptor T cell persistence and efficacy in lu...
What if brain metastatic cells do not act alone, but form #networks to help them grow?
In our new #preprint, we show that #brainmetastases form malignant, gap-junction mediated #networks that drive cell cycle progression & neural features through Ca²⁺ signaling.
www.biorxiv.org/content/10.6...
🧵👇
