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Thrilled to share our new paper out today in @NatureCancer:A single dose of RT makes CAR T cells work against extensive metastatic lung cancer — even when the target antigen is also on normal tissues. (1/14) nature.com/articles/s43018-026-01167-6
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Ahmed and colleagues show that, by promoting ‘dressing’ of intact tumor target antigens onto dendritic cells, tumor irradiation enhances chimeric antigen receptor T cell persistence and efficacy in lu...
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Tumor irradiation promotes antigen dressing of dendritic cells to enhance CAR T cell persistence and efficacy in lung metastases - Nature Cancer
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