MissAlignment is out!!! Our new software that improves reference-free tilt series alignment by mimicking human intuition. Check out Dimitry's beautiful thread for a quick summary!
And the preprint for more details: www.biorxiv.org/content/10.6...
The program: github.com/warpem/miss-...
www.biorxiv.org
Marten Chaillet
We're super excited to share MissAlignment: a new ML-based approach to reference-free tilt series alignment, spearheaded by @martenchaillet.bsky.social. We think it's going to make your cryo-ET life a lot better.
Preprint: www.biorxiv.org/content/10.6...
Code: github.com/warpem/miss-...
🧶 Thread:
Video
Rapid diagnosis of common, undetected, and uncultivable bloodstream infections from positive blood cultures using Oxford Nanopore sequencing: a metagenomic pipeline analysis - The Lancet Microbe www.thelancet.com/journals/lan...
#microsky
www.thelancet.com
These findings show that metagenomic sequencing has the potential to rapidly and comprehensively
detect pathogens and AMR in bloodstream infections. Integration into clinical practice
could help to cl...
Very happy to share our recent preprint:
“An Lsr2-like xenogeneic silencer confers immunity against AT-rich bacteriophage infection”
www.researchsquare.com/article/rs-9...
@fz-juelich.de; @hhu.de; @spp2330.bsky.social
🛠️💉It's time for engineering contractile injection systems! @chipericson.bsky.social & @davidschaumann.bsky.social introduce programmable CIS - PROCIS, combining tail length control, non-native cargo loading, and cell retargeting all in one system! www.biorxiv.org/content/10.6... 🧵 1/5
Out Now! Temperate phages enhance bacterial host fitness via RNA-guided flagellar remodelling #MicroSky
Mit dem deutschlandweit einmaligen Master-Studienschwerpunkt #Bioentrepreneurship läuten die @tu-braunschweig.de und das HZI die Zukunft der Innovation ein. Die Vertiefungsrichtung steht Studierenden aus den Biowissenschaften und Wirtschaftswissenschaften offen.
youtu.be/UqNEKTdyNmU?...
Now out in @pnas.org 🥳
"DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity"
--> bad timing can kill you, even as a virus.
www.pnas.org/doi/10.1073/...
@spp2330.bsky.social, @mibinet.bsky.social, @dfg.de
YouTube video by Technische Universität Braunschweig
youtu.be
Nature Microbiology, Published online: 27 May 2026; doi:10.1038/s41564-026-02355-xThe prophage of a clinical Enterobacter isolate uses an RNA-guided transcription factor to alter flagellar composition, leading to enhanced bacterial motility and improved gut colonization in a mouse model.
Our lab is proud to present our latest work harnessing Bridge Recombinase for genome-scale editing in diverse bacteria, microbiome editing, and programmable horizontal gene transfer.
Great piece and cover @science.org about how our field is uncovering the evolutionary and mechanistic connections between bacterial and eukaryotic immunity !
www.science.org/content/article/ancient-wars-between-microbes-gave-us-key-immune-defenses
🚨After 4 fantastic years in the Sorek lab @soreklab.bsky.social, I’ll be starting my own group at EMBL @embl.org bl.org Hamburg.
www.embl.org/groups/oster...
Metabolism-driven immunity: phages, metabolites, and discovery of new enzymes, molecules, and pathways 🦠🧬
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
