🚨After 4 fantastic years in the Sorek lab @soreklab.bsky.social, I’ll be starting my own group at EMBL @embl.org bl.org Hamburg.
www.embl.org/groups/oster...
Metabolism-driven immunity: phages, metabolites, and discovery of new enzymes, molecules, and pathways 🦠🧬
Now out in @pnas.org 🥳
"DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity"
--> bad timing can kill you, even as a virus.
www.pnas.org/doi/10.1073/...
@spp2330.bsky.social, @mibinet.bsky.social, @dfg.de
🛠️💉It's time for engineering contractile injection systems! @chipericson.bsky.social & @davidschaumann.bsky.social introduce programmable CIS - PROCIS, combining tail length control, non-native cargo loading, and cell retargeting all in one system! www.biorxiv.org/content/10.6... 🧵 1/5
Mit dem deutschlandweit einmaligen Master-Studienschwerpunkt #Bioentrepreneurship läuten die @tu-braunschweig.de und das HZI die Zukunft der Innovation ein. Die Vertiefungsrichtung steht Studierenden aus den Biowissenschaften und Wirtschaftswissenschaften offen.
youtu.be/UqNEKTdyNmU?...
Rapid diagnosis of common, undetected, and uncultivable bloodstream infections from positive blood cultures using Oxford Nanopore sequencing: a metagenomic pipeline analysis - The Lancet Microbe www.thelancet.com/journals/lan...
#microsky
Great piece and cover @science.org about how our field is uncovering the evolutionary and mechanistic connections between bacterial and eukaryotic immunity !
www.science.org/content/article/ancient-wars-between-microbes-gave-us-key-immune-defenses
Very happy to share our recent preprint:
“An Lsr2-like xenogeneic silencer confers immunity against AT-rich bacteriophage infection”
www.researchsquare.com/article/rs-9...
@fz-juelich.de; @hhu.de; @spp2330.bsky.social
MissAlignment is out!!! Our new software that improves reference-free tilt series alignment by mimicking human intuition. Check out Dimitry's beautiful thread for a quick summary!
And the preprint for more details: www.biorxiv.org/content/10.6...
The program: github.com/warpem/miss-...
Out Now! Temperate phages enhance bacterial host fitness via RNA-guided flagellar remodelling #MicroSky
These findings show that metagenomic sequencing has the potential to rapidly and comprehensively
detect pathogens and AMR in bloodstream infections. Integration into clinical practice
could help to cl...
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
Nature Microbiology, Published online: 27 May 2026; doi:10.1038/s41564-026-02355-xThe prophage of a clinical Enterobacter isolate uses an RNA-guided transcription factor to alter flagellar composition, leading to enhanced bacterial motility and improved gut colonization in a mouse model.
go.nature.com
Our lab is proud to present our latest work harnessing Bridge Recombinase for genome-scale editing in diverse bacteria, microbiome editing, and programmable horizontal gene transfer.
Nature Microbiology
Happy to share our recent preprint:
"DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity"
www.biorxiv.org/content/10.6...
@spp2330.bsky.social, @mibinet.bsky.social, @dfg.de @hhu.de @fzj.bsky.social
We're super excited to share MissAlignment: a new ML-based approach to reference-free tilt series alignment, spearheaded by @martenchaillet.bsky.social. We think it's going to make your cryo-ET life a lot better.
Preprint: www.biorxiv.org/content/10.6...
Code: github.com/warpem/miss-...
🧶 Thread:
Video
Julia Frunzke
Dimitry Tegunov
Cress Lab
Bridge recombinase enables versatile rewriting of bacterial genomes https://www.biorxiv.org/content/10.64898/2026.04.29.721476v1
