(1/7) How does T. brucei achieve a 140-fold stoichiometric excess of VSG mRNA over upstream ESAGs from a single polycistronic unit?
Our latest research in @natmicrobiol.nature.com reveals a mechanism of spatially regulated RNA decay to fine-tune expression of virulence genes
Faria Tryps Lab
Out Now! Conserved pathway for homarine catabolism in environmental bacteria #MicroSky
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Diet-microbiome analysis at population scale 💻🦠
Diet shaped gut microbiome composition and function analysed at species-level resolution might enabling long‑term predictions and personalized dietary intervention strategies.
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www.nature.com/articles/s41...
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A new way to defeat Mycobacterium! 🦠💉
Metabolic overactivation of the L‑histidine biosynthesis pathway in M. tuberculosis impairs its growth and infectivity, revealing a novel bactericidal mechanism for antimycobacterial drug discovery.
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www.nature.com/articles/s41...
Out Now! Aquatic virus transmission to humans #MicroSky
Out Now! Bacteria covalently incorporate polyfluoroalkyl carboxylates into membrane lipids #MicroSky
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Opportunistic Pseudomonas 🦠🌱
Root‑secreted coumarins can be exploited by Pseudomonas NyZ480, whose coumarin‑degrading genes enable opportunistic colonization that worsens plant iron deficiency and impairs overall plant fitness.
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www.nature.com/articles/s41...
Out Now! Specialized RNA decay fine-tunes monogenic antigen expression in Trypanosoma brucei #MicroSky
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Transmission dynamics of Oropouche virus 🌐
A comprehensive assessment of OROV transmission in 2023-24 epidemic in Manaus City & estimated OROV infections across Latin America and the Caribbean provides better understanding of the OROV burden
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www.nature.com/articles/s41...
Out Now! In the trap of Arthrobotrys #MicroSky
Nature Microbiology
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Nature Microbiology, Published online: 30 March 2026; doi:10.1038/s41564-026-02289-4To evade the immune system, Trypanosoma brucei relies on a specialized ‘expression site body’. Protein condensates within this nuclear compartment modulate expression of virulence genes via a targeted RNA decay mechanism.
Nature Microbiology, Published online: 27 March 2026; doi:10.1038/s41564-026-02306-6A human eye disease seems to be linked to covert mortality nodavirus, a virus commonly found in aquatic animals. The findings suggest that zoonotic transmission to humans occurs through close contact.
Nature Microbiology, Published online: 30 March 2026; doi:10.1038/s41564-026-02313-7Homarine is a ubiquitous, phytoplankton-derived metabolite that is broken down by widely distributed and diverse marine bacteria containing a conserved homABCDER operon.
Here, the authors show that rhizobacteria can utilize and detoxify simple coumarins secreted by iron-deficient plants, thereby enhancing their root colonization. This, in turn, hampers plant iron acqu...
Here, the authors report metabolic activation as a potential antimicrobial strategy against Mycobacterium tuberculosis. They show that supra-physiological activation of L-histidine biosynthesis r...
Analyses of more than 10,000 participants from the Human Phenotype Project revealed distinct, persistent food–microbiome associations that can be used to simulate personalized dietary interventions to...
Nature Microbiology, Published online: 27 March 2026; doi:10.1038/s41564-026-02301-xBacteria are able to covalently incorporate n:3 polyfluoroalkyl carboxylates into phosphatidylethanolamine and phosphatidylglycerol, two major components of bacterial lipid bilayers.
The transmission dynamics of the 2023–2024 Oropouche virus (OROV) outbreak in Brazil (Manaus City) revealed a twofold increase in Oropouche seroprevalence in Manaus, and in a separate historical recon...
Nature Microbiology, Published online: 27 March 2026; doi:10.1038/s41564-026-02308-4Yen-Ping Hsueh used to think she was studying a fungus that traps nematodes. Fifteen years later, she realized she was the one who had been captivated, not by adhesive hyphae but by the irresistible mystery and quiet beauty of Arthrobotrys oligospora.
