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Gut bacterial metabolism of steroid hormones Gut bacterial pathway involving OsrABC reduces natural & synthetic steroid hormones, including anti-inflammatory prednisolone. This microbial activity is enriched in Crohn’s disease patients & diminishes drug bioavailability www.cell.com/cell-host-mi...

New essay in @currentbiology.bsky.social special brain-body issue! Fly lab meets psychiatrist: how bodily signals shape cognition and mental health. Great collaboration with Albino Oliveira-Maia showing @champalimaudf.bsky.social discovery ↔️ clinic at its best. www.cell.com/current-biol...

I'm officially an expert in failing! I was asked to give the opening keynote today for a @cruk-ci.bsky.social conference, speaking on the topic "Failing in Science" youtu.be/BdrTzYcT7MY?...

What is the best brain to study disorders of behavior? Great discussion at @ecnp.eu moderated by @jatinnagpal.bsky.social with inputs from @ribeirocarlitos.bsky.social @emreyaksi.bsky.social @eknapska.bsky.social & Hannah Clarke #ecnp2025

🚀 #ALBADiversityWeek 2025 starts today! We celebrate diversity & intersectionality by highlighting key activities and sharing valuable resources. 👀 Stay tuned all week as we revisit achievements and launch new initiatives. Share our posts to join the #GlobalDiversityAwarenessMonth celebration. 🧵

Very excited to share this finding from my postdoctoral work that is now published in #ScienceAdvances. We show how the gut’s epithelium modifies enteric behaviors during nutritional adversity via distinct peptidergic signaling axes. www.science.org/doi/10.1126/... Thread ⬇️ (1/n)

Jacoby et al. identify a gut bacterial pathway that reduces natural and synthetic steroid hormones, including the anti-inflammatory drug prednisolone. This microbial activity is enriched in Crohn’s di...

Intermittent fasting enhances cognition in Alzheimer’s disease via gut microbial indole-3-propionic acid activating neuronal PXR.

Reaffirming the value of model organisms in training scientific minds | @natcellbio.nature.com www.nature.com/articles/s41...

Carlos Ribeiro and Albino Oliveira-Maia propose how brain–body interactions may inform the study of ‘higher’ cognitive functions such as learning and memory across model systems.

Had a great time discussing ‘What brain is the best to study disorders of behaviour’. Thanks to my fellow panelists and the audience for an enagaging session at European College of Neuropsychopharmacology (ECNP) 2025 meeting in Amsterdam. #ECNP2025

Great to see our review on microbiome, exposome and cognitive development out in @annualreviews.bsky.social. @apcmicrobiomeirel.bsky.social @uccresearch.bsky.social #MicrobiomeSky #Gut-Brain

Gut epithelium modulates output from distinct enteric circuits by altering secretion of insulin and noninsulin peptides.

What are the many “known unknowns” on the microbiome, exposome, & cognitive development? @maburto.bsky.social @jatinnagpal.bsky.social @jfcryan.bsky.social https://loom.ly/oUMFc0w

The gut microbiota, composed of trillions of microorganisms, plays a key role in bidirectional communication between the gut and brain, particularly during early life. The first two postnatal years represent a critical window when the exposome—the totality of all environmental exposures—shapes neurodevelopment via the microbiota–gut–brain axis. Exposome factors such as diet, birth mode, antibiotic use, infections, and xenobiotics can alter microbial composition and function, with downstream e...