Gut bacterial metabolism of steroid hormones
Gut bacterial pathway involving OsrABC reduces natural & synthetic steroid hormones, including anti-inflammatory prednisolone. This microbial activity is enriched in Crohn’s disease patients & diminishes drug bioavailability
www.cell.com/cell-host-mi...
Jacoby et al. identify a gut bacterial pathway that reduces natural and synthetic
steroid hormones, including the anti-inflammatory drug prednisolone. This microbial
activity is enriched in Crohn’s di...
