The scientific editors of Cell Host & Microbe, a Cell Press journal, bring you the latest information and insights from the forefront of host-microbe research.
Cell Host & Microbe
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Our June issue is now live.
The cover image puts microbes at play.
Have your own fun and enjoyment reading the content within:
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Co-opting cross-kingdom contact to boost bacterial pathogenicity
Preview of work evaluating bacterial-fungal co-infection of the female reproductive tract, revealing cross-kingdom co-infections can enhance pathogenicity & predisposition to infection.
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Mother knows worms: Microbes pass on antiviral defense
Preview of work showing helminth-induced remodeling of maternal microbiota can program offspring’s antiviral immunity through a microbiota-derived metabolite that enhances lung IFN-I responses
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Measles: Why the vaccine still works after 60 years
Preview of work demonstrating that vaccine-induced antibodies target highly conserved epitopes within the viral glycoproteins H and F, identifying a “vulnerability nexus” that ensures antigenic stability
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Featured Article: Colorectal adenomas leave lasting microbiome imprint
Microbial alterations detectable >10 yr after adenoma resection that resemble those in colorectal cancer, suggesting sustained host-microbiome axis along adenoma-carcinoma continuum
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Featured Article: Mom’s helminths rewire microbiota to protect offspring
Maternal helminths confer protection against respiratory viruses in offspring. Helminth-induced changes in microbiota increase indole-3-propionic acid, which induces lung IFN-I
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Fungal pathobiont boosts Streptococcus
Fungal colonization primes group B strep pathogenic potential in vaginal tract via contact-dependent nutrient sharing. Interactions w/C. albicans promote bacterial adhesion & facilitate antibiotic evasion
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Featured Article: Abs powering MMR efficacy against measles virus
Measles-specific mAbs isolated from human MMR vaccinee potently neutralize, target conserved sites & protect animals even after exposure, opening means to prevent/treat measles
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Our new paper „Variations in the latitudinal diversity gradients of the ocean microbiome“ was just published in @cp-cellhostmicrobe.bsky.social 🥳
We present a global analysis of prokaryotic #biodiversity in the surface and mesopelagic layers of the ocean 🦠🌊
www.cell.com/cell-host-mi...
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Some people taking GLP-1 drugs have experienced decreased symptoms of depression. Mouse study reveals this may be connected to GLP-1s impact on the gut microbiome.
More in Cell Host & Microbe: www.cell.com/cell-host-mi...
Honghong Yao & colleagues
@cp-cellhostmicrobe.bsky.social
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Jonas Schiller
Cell Press
In this issue of Cell Host & Microbe, Cohen and colleagues evaluate bacterial-fungal
co-infection of the female reproductive tract. They demonstrate that cross-kingdom
co-infections can lead to intric...
Fernandes et al. show that maternal helminths, long-standing mammalian partners, confer
antiviral immunity to offspring via the microbiota-derived metabolite indole-3-propionic
acid (IPA). This work r...
www.cell.com
The measles vaccine provides lifelong protection despite high virus mutation rates.
In this issue of Cell Host & Microbe, Acciani et al. demonstrate that vaccine-induced
antibodies target highly conse...
Maternal helminth exposure may confer offspring protection against respiratory viruses,
but the immune pathways and mediators are not well known. In this issue, Fernandes
et al. demonstrate that helmi...
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Nogal et al. profile the gut microbiome and metabolome of individuals with a history
of colorectal adenoma resection, revealing microbial and metabolic alterations detectable
more than a decade after ...
Acciani, Zyla et al. identify a panel of human monoclonal antibodies against measles
virus surface proteins. These antibodies neutralize with picomolar potency, target
conserved sites, broadly neutral...
Cohen et al. demonstrate that fungal colonization primes group B streptococcal pathogenic
potential in the vaginal tract through contact-dependent nutrient sharing. Interactions
with C. albicans promo...
Eriksson et al. conduct a global marine microbiome diversity analysis and demonstrate
how the surface ocean latitudinal diversity gradient is disproportionately shaped
by a few species-rich taxa. Mask...
