Measles: Why the vaccine still works after 60 years
Preview of work demonstrating that vaccine-induced antibodies target highly conserved epitopes within the viral glycoproteins H and F, identifying a “vulnerability nexus” that ensures antigenic stability
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The measles vaccine provides lifelong protection despite high virus mutation rates.
In this issue of Cell Host & Microbe, Acciani et al. demonstrate that vaccine-induced
antibodies target highly conse...