Nature Reviews Microbiology, Published online: 20 May 2026; doi:10.1038/s41579-026-01318-7The life cycle of temperate bacteriophages involves lytic or lysogenic cycles and has historically served as a model for studying genetic regulation. This Review provides an updated overview of these cycles and highlights their complexities, supporting a greater appreciation of the ecological roles of temperate phages.
dlvr.it
Nature Reviews Microbiology
"Function-specific epistasis shapes evolutionary trajectories towards antibiotic resistance". Huge parallel experimental evolution effort in E. coli under antimicrobial pressure by @gabypetrungaro.bsky.social at Bollenbach Lab at University of Cologne.
doi.org/10.1101/2025...
New paper out! 🔈
Genomic Characterization of the RyC collection: 50 Multidrug Resistant Clinical Isolates of Escherichia coli and Klebsiella spp.
50 MDR gut isolates, 2 sequencing platforms, 4 “omes,” and 1 mission: provide a resource to decode AMR and MGE dynamics
www.biorxiv.org/content/10.6...
doi.org
www.biorxiv.org
We studied the causes of #collateralsensitivity from a single enzyme perspective using and how stable such #tradeoffs are during #coselection.
In short, resistance evolution can cause strong but migigatable trade-offs.
Preproof is now available on @JMB:
www.sciencedirect.com/science/arti...
Molecular pet or parasite? Exploring selection for vertical and horizontal plasmid transfer https://www.biorxiv.org/content/10.64898/2026.06.02.729688v1
Having just finished my MCSA Fellowship with him, I would really encourage those looking to do a postdoc in microbial adaptation to check out Alex Couces lab in Madrid. Alex is a gifted researcher, and Madrid is a wonderful city to live in :) Details in link below:
evoldir.net/brian/evoldi...
Alf Soler-Bistué 🦠🔬🧫
Paloma Rodera
A livestream of a volcano in the Philippines captured a meteor crashing to Earth today. What are the odds?
Mayon Volcano, Location: Albay, Luzon, Philippines
Our study comparing promoter existence and emergence in random vs genomic DNA is finally published!!!
TLDR: the E. coli genome has more promoters than random DNA (even in intergenic regions), and promoters emerge ~3x more readily from random DNA than genomic DNA. (1/2)
Video
Happy to share that our latest research on the eco-evolutionary dynamics of MDR plasmids and PDPs is now out (open access vAuthor) in The ISME Journal doi.org/10.1093/isme...
Here, we explored how plasmid-dependent phages (PDPs) act as a selective pressure against the spread of multidrug resistance
Promoters emerge three times more readily from random DNA than from genomic DNA.
Abstract. Phage therapy offers a promising alternative to antibiotics for treating multidrug-resistant infections. Plasmid-dependent phages (PDPs) are part
