I had the pleasure of presenting concepts of T cell immunity and our work on cancer immune evasion at the @dgfi-org.bsky.social Spring School in Ettal, Bavaria. Inspiring talks & great exchanges with talented junior researchers across Germany—thank you for the invitation! #dgfispringschool
Excited to share our new collaborative study with the Sebastian Kobold lab! www.nature.com/articles/s41...
By deleting the PGE2 receptors EP2/EP4, we render CAR T cells resistant to suppression in solid tumors - boosting persistence and anticancer activity in preclinical models and patient samples.
Thrilled to share that my #ERCCoG EICO-CODE has been selected for funding!🚀 We will study how eicosanoids shape T cell immunity across tissues. 🧬🔬🧪✨ I am deeply grateful for this recognition of the team’s work - and to everyone supporting us in our research. Exciting years ahead!
Less than one week left to apply 🔜
🚨Our lab has a new review article out today!
We revisit prostaglandins in cancer—how they’re produced, how PGE₂ reshapes immune responses in tumors, and what this means for future therapies.
Work led by team members Erik Müller & Bastian Kruse @bkru.bsky.social
🔗 doi.org/10.1182/bloo...
Interesting study by @reisesousalab.bsky.social, highlighting functionally distinct states of activated cDC1s in tumors. 🔬🧪