Professor of Experimental Immunology at the University of Tübingen, M3 Research Center & Institute of Immunology. 🧪🔬 Interested in immunity in cancer and infection. Fascinated by dendritic cells, T cells and NK cells
Jan Böttcher
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I had the pleasure of presenting concepts of T cell immunity and our work on cancer immune evasion at the @dgfi-org.bsky.social Spring School in Ettal, Bavaria. Inspiring talks & great exchanges with talented junior researchers across Germany—thank you for the invitation! #dgfispringschool
Excited to share our new collaborative study with the Sebastian Kobold lab! www.nature.com/articles/s41...
By deleting the PGE2 receptors EP2/EP4, we render CAR T cells resistant to suppression in solid tumors - boosting persistence and anticancer activity in preclinical models and patient samples.
Thrilled to share that my #ERCCoG EICO-CODE has been selected for funding!🚀 We will study how eicosanoids shape T cell immunity across tissues. 🧬🔬🧪✨ I am deeply grateful for this recognition of the team’s work - and to everyone supporting us in our research. Exciting years ahead!
Less than one week left to apply 🔜
Very happy to join the team of the CRC 1479 initiative for the 2nd funding period to study mechanisms of immune evasion in cancer! www.sfb1479.uni-freiburg.de/news/great-n...
🚨Our lab has a new review article out today!
We revisit prostaglandins in cancer—how they’re produced, how PGE₂ reshapes immune responses in tumors, and what this means for future therapies.
Work led by team members Erik Müller & Bastian Kruse @bkru.bsky.social
🔗 doi.org/10.1182/bloo...
Idoyaga and colleagues suggest that pDCs can lose the ability to secrete IFN-I and acquire the transcriptional, epigenetic and functional features of cDCs. Read it here: rdcu.be/eBB5e
www.nature.com/articles/s41...
