New Paper in Science Advances: Researchers at JMU discovered that a molecule can act as a biological “double agent”: while blocking one important #cell process, it also disables a key protective mechanism. #CellBiology #Pharmakology
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➡️ go.uniwue.de/gohla-cp1
📍 Registration is now open for this #Redox #BiochemicalSociety Meeting! Excellent invited speakers, plus many slots for elevated talks from abstracts, including #ECRs 🫵
🌍 Cambridge, UK
🗓️ 16-18 Nov 2026
⏳ Super early bird deadline: 16 Aug 2026
🌐 bit.ly/Redox-26
#BiochemEvent
@biochemsoc.bsky.social
happy to share our review collection “Metabolic Reprogramming in Cancer: Mechanisms and Therapeutic Opportunities” @oncogenesisnature.bsky.social . A big thank you to all contributing authors. If you are interested in cancer metabolism, I encourage you to read these expert reviews. enjoy!!
Julius-Maximilians-Universität Würzburg
Pleased to share our recent work out today in @natmetabolism.nature.com. This study addresses a longstanding mystery - NRF2-driven cancers increase cysteine acquisition (via xCT) by ~5x - so where does all that cysteine go?
Online now! Online now! The molecular basis for nuclear pore destruction by a proximity-inducing molecular glue #chembiol
Hinshaw et al. determine the molecular basis for TRIM21 recruitment to the nuclear pore protein NUP98, showing that an induced protein-protein interface drives the potency and selectivity of the molecular glue mechanism.
Excellent and highly insightful review - A must-read for researchers interested in lymphoma and cancer metabolism.
Thank you Chris for contributing to our special issue in @oncogenesisnature.bsky.social on « metabolism and cancer »
www.nature.com/articles/s41...
Oncogenesis - Metabolic vulnerabilities and therapeutic opportunities in diffuse large B-cell lymphoma
If you are a postdoc or grad students that wants to be considered for a talk at the GRS then get your abstract in! (Deadline 5th April).
Jean-Ehrland RICCI
“Fatty acid channelling into triglycerides and oxylipins drives ferroptosis resistance during oncogenic BRAF-induced senescence”
An interesting link between lipid metabolism in OIS cells and their resistance to ferroptosis and oxidative stress ⤵️
www.nature.com/articles/s41...
🚀📚 Excited to share the launch of the review collection "Metabolic Reprogramming in Cancer: Mechanisms and Therapeutic Opportunities", edited by Shensi Shen (@seansi.bsky.social) and Jean-Ehrland Ricci (@jer-06.bsky.social).
📖 Discover the Review Collection: www.nature.com/collections/...
If a week by the Mediterranean discussing the latest research Bridging Redox Chemistry to Biology, Aging and Disease sounds like a welcome escape, then this Gordon Research Conference could be for you! www.grc.org/thiol-based-...
Join us in Cambridge from 16-18 November 2026 to celebrate the latest research in redox biology! Featuring insights into redox regulation, metabolism, cell death, hypoxia and more. Organised by @cochemelab.bsky.social, @jamesnathanlab.bsky.social, Phil Eaton and Andy Finch: https://ow.ly/UbTJ50YZxFg
Nature Metabolism, Published online: 07 April 2026; doi:10.1038/s42255-026-01499-8Previously uncharacterized cysteine-derived conjugates, including with endogenous sugar metabolites, accumulate in cancer cells with constitutive NRF2 activation and account for some of the increased cystine uptake that cannot be explained by conventional cysteine metabolism.
The 2026 Gordon Research Conference on Thiol-Based Redox Regulation and Signaling will be held in Castelldefels, Barcelona Spain. Apply today to reserve your spot.
