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Online now! Online now! The molecular basis for nuclear pore destruction by a proximity-inducing molecular glue #chembiol
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Hinshaw et al. determine the molecular basis for TRIM21 recruitment to the nuclear pore protein NUP98, showing that an induced protein-protein interface drives the potency and selectivity of the molecular glue mechanism.
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The molecular basis for nuclear pore destruction by a proximity-inducing molecular glue
Cell Chemical Biology