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Very excited to share our new paper out in Nature. Congrats to Xiaoqian (Annie) Yu and all the coauthors. www.nature.com/articles/s41...
Milliardenkürzungen bei Unis? Das hätte massive Folgen für die Steiermark! Setzen wir bei den Demos ein Zeichen: 🟢 Wien: 27. Mai 2026, 13 Uhr, Hauptgebäude der Universität Wien, Universitätsring 1​ 🟢 Graz: 28. Mai 2026, 14.30 Uhr, Wilhelm-Fischer-Allee am Stadtpark, Graz #unisretten
Interesting article by Glass et al. on using metabolic modeling to find new antibiotics for the vaginal microbiome.
1mo
How every layer of science's "self-correcting machinery" failed when Iva Veseli and I simply wanted to reproduce the findings of a high-profile study on gut microbiome and autism: merenlab.org/2026/04/15/u...
New online! Sequencing what we eat
1d
Paper out: Profiling of lytic phage infection in individual B. fragilis cells with bacterial scRNA-seq. Congratulations Anika Gupta, Norma Morella, @monochamussutor.bsky.social Dmitry Sutormin et al, in collaboration with Georg Seelig (UW) and Neel Dey (Fred Hutch). www.nature.com/articles/s41...
New online! Next-generation probiotics: an outlook into current applications and future developments
Microbial communities can harbor many species that do not coexist in pairs, yet can coexist in the full community. Here we provide the mathematical foundations of emergent coexistence, and explain why it can't be predicted from pairwise tests journals.plos.org/ploscompbiol...
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Genome-wide selective sweeps commonly occur in the human gut microbiome and can spread across the world within decades to produce epidemic-like population structures.
www.nature.com
I like how all the p-values are like 10^-300. Take that power analysis.
Genome-wide sweeps create ecological units in the human gut microbiome - Nature
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Sequencing what we eat
Nature Reviews Gastroenterology & Hepatology, Published online: 19 May 2026; doi:10.1038/s41575-026-01215-7Dietary assessment commonly relies on asking people what they remember eating. Genomic methods can change this assessment, paralleling how DNA sequencing revolutionized microbiology. By identifying consumed foods directly from stool, these approaches offer an objective, scalable alternative that gastroenterology researchers can begin using today.
dlvr.it
The myth of open data, reproducibility, responsibility, and accountability in science, and your role in it
merenlab.org
Unfalsifiable by Design: A Year of Trying and Failing to Reproduce a Human Microbiome and Autism Study
Phage-bacteria interactions are typically studied in bulk culture, which obscures cell-cell differences. Here the authors study phage-bacteria interactions using single-cell transcriptomics, identifyi...
www.nature.com
Nature Reviews Microbiology, Published online: 08 May 2026; doi:10.1038/s41579-026-01311-0In this Review, Kern, Tofield, Frame and Elinav discuss recent advances in the design of next-generation probiotics, from identification of candidates to therapeutic applications across diverse disease contexts, and highlight major challenges and the potential of artificial intelligence to develop effective, personalized probiotics with therapeutic functions.
dlvr.it
Dynamics of phage-host interactions in Bacteroides fragilis resolved by single-cell transcriptomics - Nature Communications
Next-generation probiotics: an outlook into current applications and future developments
Martin Polz
Nature Reviews Gastroenterology & Hepatology
Medizinische Universität Graz
Guim Aguadé-Gorgorió
Christian Diener
Christian Diener
A. Murat Eren (Meren)
Anna Kuchina
Nature Reviews Microbiology
Out Now! Genome-scale metabolic modelling identifies vaginal microbiome members as potential probiotics #MicroSky
3d
Indeed.. here is "generate the first page of a great Nature paper that will get lots of citations. It must be very novel."
Nature Microbiology, Published online: 12 June 2026; doi:10.1038/s41564-026-02380-wMetabolic modelling and experimental validation reveal that current probiotics lack the functional diversity of native microbes, identifying vaginal species that inhibit Gardnerella vaginalis through the dual mechanisms of resource competition and d-lactic acid production.
go.nature.com
1mo
Genome-scale metabolic modelling identifies vaginal microbiome members as potential probiotics
Nature Microbiology
Theo Sanderson