Excited to share our new paper!
This work explores how Sonic hedgehog signaling helps coordinate retinal patterning and neurogenesis, including regulation of both cell cycle exit and progenitor competence during mammalian eye development journals.biologists.com/dev/article/...
Join us in Toronto, July 13–16 for the International Conference on Neurogenesis and Repair.
Featuring keynote Dr. Jeffrey Macklis (Harvard), 13 short‑talk slots, poster sessions, and many trainee travel awards
Details + registration:
event.fourwaves.com/neurogenesis...
Hope to see you there!
New paper out 🚨! Excited to share this collab between my lab and @kerschensteiner.bsky.social's group, expertly led by Ning Shen. We used a genome-wide in vivo CRISPR screen to uncover novel neuroprotective strategies in the P23H mouse retina, with validation in a new human retina culture model.
New study led by Ning Shen w/ @phruzycki.bsky.social: a genome-wide in vivo CRISPR screen in a retinitis pigmentosa mouse model identifies genes whose loss accelerates photoreceptor death. Overexpressing two, UFD1 and UXT, preserves photoreceptors, retinal function, and vision. 🧵
New paper out! 🚨
We show that Ndufs4 loss triggers retinal neurodegeneration through a phased process.
A new window into neuroimmune mechanisms in mitochondrial disease: link.springer.com/article/10.1...
The 2026 Visual System Development GRC and GRS are fast approaching. Jeremy Kay, Kristen Kwan, Robert Johnston, and I have built an exciting program that we hope you will enjoy. Looking forward to seeing everyone at the meeting this summer in beautiful Maine. Register and RT!
Excited to share our new manuscript from the Yoshimatsu and MacDonald labs. www.biorxiv.org/content/10.6.... We found that my favourite glial cells can regulate local retinoic acid signalling to specialise cone photoreceptors for high acuity visual function.
*THE best
Congratulations!!! That’s amazing (and well deserved I’m sure!)