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New paper out! 🚨 We show that Ndufs4 loss triggers retinal neurodegeneration through a phased process. A new window into neuroimmune mechanisms in mitochondrial disease: link.springer.com/article/10.1...
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Journal of Neuroinflammation - Mitochondrial dysfunction is a central hallmark of many optic neuropathies, yet the mechanisms linking intrinsic metabolic stress to retinal ganglion cell (RGC)...
link.springer.com
Cell-intrinsic vulnerability and immune activation cooperate to drive degeneration in a mitochondrial complex I deficiency model of optic neuropathy - Journal of Neuroinflammation
Anna La Torre