Great progress being made to understand mechanisms contributing to #HFpEF
Fantastic talks from @rebeccahritchie.bsky.social & others at the #ishr2025 meeting in Nara
#cardiosky @davorpavlovic.bsky.social @monikagladka.bsky.social @jmccardiology.bsky.social @jmccplus.bsky.social
Good morning #ISHR2025! Stop by our booth in the exhibition area to learn more about JMCC and @jmccplus.bsky.social.
Hope to see you in Nara!
Dr Kate Weeks
Journal of Molecular and Cellular Cardiology
Did you know heart muscle cells can have multiple nuclei? (See the pic on my profile for an example!)
Within each nucleus, there can also be multiple sets of chromosomes (polyploidy). 🧬🧬🧬🧬
This new paper in @jmccardiology.bsky.social describes a new method for assessing ploidy in cardiomyocytes. 🔬
In our April issue, Orlowski and colleagues describe for the first time that IRBIT plays a critical role in the pathophysiology of the heart.
Cardiac hypertrophy induced by overexpression of IP3-released inositol 1, 4, 5-trisphosphate receptor-binding protein (IRBIT) : buff.ly/czTyHDW
Work in our April issue offers a detailed cardioFISH protocol for #cardiomyocyte nuclear ploidy assessment.
Available open access: doi.org/10.1016/j.yj...
Editor's Choice! Autoinhibition of cMyBP-C by its middle domains: www.sciencedirect.com/science/arti...
Our journal reception at #ISHR2025 included recognition of Rong Tian for her service as Editor in Chief of JMCC. Her term ends in December 2025. Congratulations Rong for your excellent work on the journal!
Dr Kate Weeks
Journal of Molecular and Cellular Cardiology
Journal of Molecular and Cellular Cardiology
Journal of Molecular and Cellular Cardiology
Journal of Molecular and Cellular Cardiology
Great opening ceremony of the #ISHR2025 XXV World Congress in Nara. Excited to discuss science with colleagues of the Cardiovascular field during this ISHR meeting.
NicolasAvilaLab
Looking for some weekend reading or on your way to the
ISHR meeting in Japan?
Check out the recent work from Alican Guran,
@k8weeks.bsky.social et al. investigating the role of B56α as a mediator of cardiac responses to β-AR stimulation!
sciencedirect.com/science/arti...
JMCC Plus
Dr Zijing Zhou’s drive to understand the fundamental biological processes at work within the heart has led him to study ion channels that may be the key to managing not only cardiac diseases, but also osteoporosis, obesity and inflammatory diseases: www.victorchang.edu....
Work in our April issue offers a detailed cardioFISH protocol for #cardiomyocyte nuclear ploidy assessment.
Available open access: doi.org/10.1016/j.yj...
Journal of Molecular and Cellular Cardiology
Victor Chang Cardiac Research Institute
B56α is a protein phosphatase 2 A (PP2A) regulatory subunit which modulates the heart's inotropic response to acute β-adrenergic receptor (β-AR) stimu…
