How do cells cope with stress?
Explore the molecuar details of cellular stress responses in Prof. Christian Münch’s group(@cmunch.bsky.social, @goetheuni.bsky.social). All details and the application portal are available on our website:👉 imprs-cbp.mpg.de/call-for-app... #phd #biophysics #cellbiology
Super excited to share our latest work on deciphering the #Ubiquitin Code
“𝗨𝗯𝗶𝗥𝗘𝗔𝗗 𝗱𝗲𝗰𝗶𝗽𝗵𝗲𝗿𝘀 𝗽𝗿𝗼𝘁𝗲𝗮𝘀𝗼𝗺𝗮𝗹 𝗱𝗲𝗴𝗿𝗮𝗱𝗮𝘁𝗶𝗼𝗻 𝗰𝗼𝗱𝗲 𝗼𝗳 𝗵𝗼𝗺𝗼𝘁𝘆𝗽𝗶𝗰 𝗮𝗻𝗱 𝗯𝗿𝗮𝗻𝗰𝗵𝗲𝗱 𝗞48 𝗮𝗻𝗱 𝗞63 𝘂𝗯𝗶𝗾𝘂𝗶𝘁𝗶𝗻 𝗰𝗵𝗮𝗶𝗻𝘀”
@cp-molcell.bsky.social
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www.cell.com/molecular-ce...
🎉 We’re absolutely thrilled: SCALE has been selected as a DFG Excellence Cluster!
A huge thank you to our incredible team—this would not have been possible without your dedication and talent. 🙌 @dfg.de
#ClustersOfExcellence #SCALEcluster 🧵
🗺️ Interactive Map Update!
The Münch Lab @cmunch.bsky.social has joined the global TPD map! 🎉
Explore their work and discover other labs studying #TPD and #ubiquitin biology.
👉 tpd-community.com
#ProteinDegradation
🎉 In the final round of the ExStra Program of the DFG, the CPI has been selected & is honored with funding for another 7 years! 🏆 With the vision that “precision biology drives precision medicine”, funds will be used for high-risk, innovative research for cardiopulmonary health ❤️🫁!
Fantastic work and important inside into a longstanding question!
Have a look at our newest commentary in @pnas.org :
"G-quadruplexes and their unexpected ability to fold proteins"
Full text: www.pnas.org/doi/10.1073/...
#G4 #quadruplex #proteins #folding
Rupert Beale @bealelab.bsky.social and co-workers @crick.ac.uk @imperialcollegeldn.bsky.social show that #caspase cleavage of #influenza A #virus M2 disrupts M2-LC3 interaction and regulates virion production.
-> www.embopress.org/doi/full/10....
Less than a week left to apply to the open post doc position in our lab. Join us in beautiful Gothenburg to work on an exciting project!
www.nature.com/naturecareer...
I am overjoyed to present our latest paper on Autophagy in CD8 Tcells!
www.nature.com/articles/s41...
It was, as all ‘sciencing’ is, a huge team effort.
I will try to do it some justice in the following thread 😊 1/n
@cantrell-lab.bsky.social @immpres.bsky.social @ajmhowden.bsky.social
Ubiquitin chains determine the fates of their modified proteins, including proteasomal
degradation. Kiss et al. present UbiREAD, a technology to monitor cellular degradation
and deubiquitination at hi...
www.cell.com
G-quadruplexes and their unexpected ability to fold proteins
Sinclair et al. combine quantitative proteomics and an autophagy flux reporter to map autophagy substrates and triggers during CD8 T cell differentiation. Proteins degraded and fueled by autophagy in ...
Exciting news from the lab out today in Science - the structure of human PINK1 on a TOM-VDAC complex!
@wehi-research.bsky.social
Komander Lab
Thrilled to share the structure of dimerised human PINK1 docked to an endogenous translocase array on the mitochondrial surface, composed of two TOM complexes, bridged by a VDAC2 dimer! Published today in Science www.science.org/doi/10.1126/...
@wehi-research.bsky.social @komanderlab.bsky.social