Professor at Goethe University Frankfurt || proteostasis, mitochondria, autophagy, protein quality control, translation, infection, cancer, neurodegeneration || proteomics, molecular systems biology, cell biology || https://molsysmed.de
Christian Münch
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Fantastic work and important inside into a longstanding question!
🎉 In the final round of the ExStra Program of the DFG, the CPI has been selected & is honored with funding for another 7 years! 🏆 With the vision that “precision biology drives precision medicine”, funds will be used for high-risk, innovative research for cardiopulmonary health ❤️🫁!
Christian Münch
How do cells cope with stress?
Explore the molecuar details of cellular stress responses in Prof. Christian Münch’s group(@cmunch.bsky.social, @goetheuni.bsky.social). All details and the application portal are available on our website:👉 imprs-cbp.mpg.de/call-for-app... #phd #biophysics #cellbiology
Ubiquitin chains determine the fates of their modified proteins, including proteasomal
degradation. Kiss et al. present UbiREAD, a technology to monitor cellular degradation
and deubiquitination at hi...
🗺️ Interactive Map Update!
The Münch Lab @cmunch.bsky.social has joined the global TPD map! 🎉
Explore their work and discover other labs studying #TPD and #ubiquitin biology.
👉 tpd-community.com
#ProteinDegradation
Less than a week left to apply to the open post doc position in our lab. Join us in beautiful Gothenburg to work on an exciting project!
www.nature.com/naturecareer...
Have a look at our newest commentary in @pnas.org :
"G-quadruplexes and their unexpected ability to fold proteins"
Full text: www.pnas.org/doi/10.1073/...
#G4 #quadruplex #proteins #folding
Rupert Beale @bealelab.bsky.social and co-workers @crick.ac.uk @imperialcollegeldn.bsky.social show that #caspase cleavage of #influenza A #virus M2 disrupts M2-LC3 interaction and regulates virion production.
-> www.embopress.org/doi/full/10....
Leo Kiss
🎉 We’re absolutely thrilled: SCALE has been selected as a DFG Excellence Cluster!
A huge thank you to our incredible team—this would not have been possible without your dedication and talent. 🙌 @dfg.de
#ClustersOfExcellence #SCALEcluster 🧵
Cardio-Pulmonary Institute | CPI
IMPRS on Cellular Biophysics
Targeted protein degradation community
Martin Ott lab
Schwalbe Lab
EMBO Reports
SCALE - SubCellular Architecture of LifE
Exciting news from the lab out today in Science - the structure of human PINK1 on a TOM-VDAC complex!
@wehi-research.bsky.social
www.nature.com
Investigating the molecular connectivity of mitochondrial gene expression, protein biogenesis and quality control Background: Mitochondria convert ...
I am overjoyed to present our latest paper on Autophagy in CD8 Tcells!
www.nature.com/articles/s41...
It was, as all ‘sciencing’ is, a huge team effort.
I will try to do it some justice in the following thread 😊 1/n
@cantrell-lab.bsky.social @immpres.bsky.social @ajmhowden.bsky.social
Sinclair et al. combine quantitative proteomics and an autophagy flux reporter to map autophagy substrates and triggers during CD8 T cell differentiation. Proteins degraded and fueled by autophagy in ...
Thrilled to share the structure of dimerised human PINK1 docked to an endogenous translocase array on the mitochondrial surface, composed of two TOM complexes, bridged by a VDAC2 dimer! Published today in Science www.science.org/doi/10.1126/...
@wehi-research.bsky.social @komanderlab.bsky.social