Professor at Goethe University Frankfurt || proteostasis, mitochondria, autophagy, protein quality control, translation, infection, cancer, neurodegeneration || proteomics, molecular systems biology, cell biology || https://molsysmed.de
Christian Mรผnch
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Fantastic work and important inside into a longstanding question!
๐ In the final round of the ExStra Program of the DFG, the CPI has been selected & is honored with funding for another 7 years! ๐ With the vision that โprecision biology drives precision medicineโ, funds will be used for high-risk, innovative research for cardiopulmonary health โค๏ธ๐ซ!
Have a look at our newest commentary in @pnas.org :
"G-quadruplexes and their unexpected ability to fold proteins"
Full text: www.pnas.org/doi/10.1073/...
#G4 #quadruplex #proteins #folding
Super excited to share our latest work on deciphering the #Ubiquitin Code
โ๐จ๐ฏ๐ถ๐ฅ๐๐๐ ๐ฑ๐ฒ๐ฐ๐ถ๐ฝ๐ต๐ฒ๐ฟ๐ ๐ฝ๐ฟ๐ผ๐๐ฒ๐ฎ๐๐ผ๐บ๐ฎ๐น ๐ฑ๐ฒ๐ด๐ฟ๐ฎ๐ฑ๐ฎ๐๐ถ๐ผ๐ป ๐ฐ๐ผ๐ฑ๐ฒ ๐ผ๐ณ ๐ต๐ผ๐บ๐ผ๐๐๐ฝ๐ถ๐ฐ ๐ฎ๐ป๐ฑ ๐ฏ๐ฟ๐ฎ๐ป๐ฐ๐ต๐ฒ๐ฑ ๐48 ๐ฎ๐ป๐ฑ ๐63 ๐๐ฏ๐ถ๐พ๐๐ถ๐๐ถ๐ป ๐ฐ๐ต๐ฎ๐ถ๐ป๐โ
@cp-molcell.bsky.social
1/8
www.cell.com/molecular-ce...
How do cells cope with stress?
Explore the molecuar details of cellular stress responses in Prof. Christian Mรผnchโs group(@cmunch.bsky.social, @goetheuni.bsky.social). All details and the application portal are available on our website:๐ imprs-cbp.mpg.de/call-for-app... #phd #biophysics #cellbiology
๐บ๏ธ Interactive Map Update!
The Mรผnch Lab @cmunch.bsky.social has joined the global TPD map! ๐
Explore their work and discover other labs studying #TPD and #ubiquitin biology.
๐ tpd-community.com
#ProteinDegradation
๐ Weโre absolutely thrilled: SCALE has been selected as a DFG Excellence Cluster!
A huge thank you to our incredible teamโthis would not have been possible without your dedication and talent. ๐ @dfg.de
#ClustersOfExcellence #SCALEcluster ๐งต
I am overjoyed to present our latest paper on Autophagy in CD8 Tcells!
www.nature.com/articles/s41...
It was, as all โsciencingโ is, a huge team effort.
I will try to do it some justice in the following thread ๐ 1/n
@cantrell-lab.bsky.social @immpres.bsky.social @ajmhowden.bsky.social
Rupert Beale @bealelab.bsky.social and co-workers @crick.ac.uk @imperialcollegeldn.bsky.social show that #caspase cleavage of #influenza A #virus M2 disrupts M2-LC3 interaction and regulates virion production.
-> www.embopress.org/doi/full/10....
Less than a week left to apply to the open post doc position in our lab. Join us in beautiful Gothenburg to work on an exciting project!
www.nature.com/naturecareer...
G-quadruplexes and their unexpected ability to fold proteins
www.pnas.org
Ubiquitin chains determine the fates of their modified proteins, including proteasomal
degradation. Kiss etย al. present UbiREAD, a technology to monitor cellular degradation
and deubiquitination at hi...
Sinclair et al. combine quantitative proteomics and an autophagy flux reporter to map autophagy substrates and triggers during CD8 Tโcell differentiation. Proteins degraded and fueled by autophagy in ...
Exciting news from the lab out today in Science - the structure of human PINK1 on a TOM-VDAC complex!
@wehi-research.bsky.social
Komander Lab
Thrilled to share the structure of dimerised human PINK1 docked to an endogenous translocase array on the mitochondrial surface, composed of two TOM complexes, bridged by a VDAC2 dimer! Published today in Science www.science.org/doi/10.1126/...
@wehi-research.bsky.social @komanderlab.bsky.social
