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📢Magda Koziol @epigenome.bsky.social will be speaking at the DPZ @primatenzentrum.bsky.social in Göttingen this Wednesday. 🗓️11 March ⏰13:00 Join us for an exciting seminar! 👇👇
3mo
Great to see this work out from our neighbours @mrc-lms.bsky.social driven by Noura Maziak @vaquerizasjm.bsky.social! With Pico-C they reveal a modular regulatory logic driving genome establishment - congrats to all authors!
3mo
We are hiring POSTDOC now!🚨please repost! Fully-funded 5-year position 👩🏻‍🔬👨‍🔬🧬Looking forward to your application!✉️
3mo
Exciting breakthrough technology from the lab, now live in @cellcellpress.bsky.social ! Instead of cutting the genome where proteins bind (e.g., Cut&Tag), D&D-seq scars the DNA with a deaminase, allowing single cell genome mapping of TFs and chromatin remodellers!
17d
Enhancers are genetic regions that promote the activation of neighbouring genes. @radaiglesiaslab.bsky.social asks how long-range enhancers maintain specificity by constructing synthetic gene landscapes and exploring how they affect gene activity. #gfe2026 Alvaro's @dev-journal.bsky.social Review⤵
3mo
Summary: This Review discusses recent insights into the factors controlling enhancer specificity and how this might help us understand the genetic basis of human disease.
doi.org
Enhancer-gene specificity in development and disease
Ufuk Günesdogan
Vicki Metzis
Takashi Akera Lab
Nucleosome aficionados! Our new review "Nucleosome spacing across cell types, diseases, and ages" is out in NAR: academic.oup.com/nar/article/... A huge effort to pull together what we’ve learned about nucleosome spacing in many systems. Enjoy! @milena-bikova.bsky.social @chrsclrksn.bsky.social
3mo
Dan Landau
Very excited to share our newest findings! A very long team effort pursued by multiple team members -to frantically reproduce everything over and over-, we show mTOR-Polycomb synergy at promoters of developmental master regulator TFs in ESCs prior to their expression. www.biorxiv.org/content/10.6...
Alex Eve
1mo
Friends Davor Solter and Azim Surani receiving the wonderful Paul Ehrlich and Ludwig Darmstaedter Prize for Genomic Imprinting👏 👍 @Frankfurt Germany. With official talks from politicians using words like Education, Knowledge, Democracy 🙏 @maxplanck.de @gurdoninstitute.bsky.social
🚨The abstract submission deadline is this Friday 17 April 2026.
3mo
2mo
De novo formation of cis-regulatory contacts in the absence of NIPBL-driven chromatin loop extrusion www.nature.com/articles/s41...
www.biorxiv.org
2mo
The authors deplete the cohesin activator NIPBL during the mitosis-to-G1-phase transition. They observe that structural loop formation is impaired proportionally to loop length, while gene activation ...
www.nature.com
De novo formation of cis-regulatory contacts in the absence of NIPBL-driven chromatin loop extrusion - Nature Genetics
3mo
Excited to share my PhD work! The question: How is genome organization established? Here, we developed a low-input Micro-C method, Pico-C, and used it to map chromatin architecture across early stages of fly development. Here’s a quick Blue-torial 🙂 (1/n) www.nature.com/articles/s41...
Pico-C, a low-input Micro-C approach, reveals that dynamic three-dimensional genome folding precedes zygotic genome activation in Drosophila.
www.nature.com
Three-dimensional genome reorganization foreshadows zygotic genome activation in Drosophila - Nature Genetics
Teif lab
Denis Duboule
the Node
Aydan Bulut-Karslioglu
Evgeny Kvon
Noura Maziak
Mark your calendars! The @lscn.bsky.social 9th Annual Symposium is happening on 15 May – and it's shaping up to be an unmissable day of cutting-edge science, collaboration, & community! A great line-up has also been announced. www.eventbrite.co.uk/e/9th-annual...
2mo
the Node
Join us for The London Stem Cell Network's 9th Annual Symposium at Bush House (30 Aldwych, London, WC2B 4BG) on Friday 15th May 2026.
www.eventbrite.co.uk
9th Annual London Stem Cell Network Symposium