Great to see this work out from our neighbours @mrc-lms.bsky.social driven by Noura Maziak @vaquerizasjm.bsky.social!
With Pico-C they reveal a modular regulatory logic driving genome establishment - congrats to all authors!
Vicki Metzis
Excited to share my PhD work!
The question: How is genome organization established? Here, we developed a low-input Micro-C method, Pico-C, and used it to map chromatin architecture across early stages of fly development.
Here’s a quick Blue-torial 🙂 (1/n)
www.nature.com/articles/s41...
Pico-C, a low-input Micro-C approach, reveals that dynamic three-dimensional genome folding precedes zygotic genome activation in Drosophila.