If you want to know what 3′UTRs with long conserved sequence stretches do, check out our BioRxiv preprint doi.org/10.64898/202....
They form functional intermolecular 3′UTR-3′UTR interactions that enable co-folding of proteins to rapidly induce transcriptional programs.
Christine Mayr
This is a very big deal, awesome work!
Jonathan Keats, PhD 🇨🇦
In case you missed it: last night, CBS News awarded the Mike Wallace Memorial Scholarship to Santiago Campos, a high school journalist. In accepting, he took the time to condemn the direction of CBS News to much surprise and applause from the audience.
Video
William "Chip" Nagel
Charlotte Clymer
A new paper reports identification of a binder of IRF4 and development of a selective degrader that exhibits strong cytotoxicity against multiple myeloma cell lines
www.nature.com/articles/s41...
Identification of a binder of interferon regulatory factor 4 (IRF4) enabled development of a selective degrader, dIRF4-2, that exhibited strong cytotoxicity in multiple myeloma cell lines, offering an...