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A new paper reports identification of a binder of IRF4 and development of a selective degrader that exhibits strong cytotoxicity against multiple myeloma cell lines www.nature.com/articles/s41...
www.nature.com
Identification of a binder of interferon regulatory factor 4 (IRF4) enabled development of a selective degrader, dIRF4-2, that exhibited strong cytotoxicity in multiple myeloma cell lines, offering an...
Pharmacological targeting of IRF4 as a therapeutic strategy for multiple myeloma - Nature Chemical Biology
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Nature Chemical Biology