Rendez-vous à Autrans en juin pour échanger autour d'applications de nos spins préférés ! 👇
The 14th #NMR a tool for biology conference was a big success, thanks to the contributions of our 200 attendees from 18 countries, and 40% of students/postdocs. The future of NMR is in good hands. 🥰
Have a safe trip back home. See you @pasteur.fr on May 10-12, 2027 @brukercorporation.bsky.social
Please RT. Join the sixth edition of our Training Unit @institut_curie
international course on Genome Instability & Human Disease open to master students, PhDs and researchers! Amazing program. Registration dead line 2nd March 2025 at training.institut-curie.org/courses/geno...
Our new preprint! (reposted with tags 🧬🧶)
We investigated how protein-RNA interface structure evolves by thoroughly analyzing the conservation of contacts among 2022 pairs of homologous interfaces. Work with Ikram Mahmoudi, Chloé Quignot, Carla Martins
🚨 I am super happy to announce that our analysis of how the structure of protein-RNA interfaces evolves is now published (early access) at @plos.bsky.social Computational Biology:
doi.org/10.1371/jour...
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(1/2) Thrilled to share our findings on the assembly of the Rad51 recombinase filament in Saccharomyces cerevisiae. This work is the result of a wonderful collaboration with Eric Coïc's team at CEA Fontenay-aux-Roses and Angela Taddei's team at the Institut Curie.
www.biorxiv.org/content/10.1...
A pleasure to reconnect with the 3R community - Replication, Repair and Recombination - at the 16th 3R Meeting in La Grande-Motte, 18-21 May 2026. Thanks to all for the great science, discussions and atmosphere, and to our sponsors. See you in two years! #3RMeeting #ReplicationRepairRecombination
2) The histone chaperone CAF1 promotes PRIMPOL recruitment to restart stalled forks through ssDNA gap formation. doi.org/10.1093/nar/...
(2/2)Through integrative structural and functional analyses, we identified a large disordered segment of Rad52 that binds Rad51 and functions as an assembly chaperone. It prevents Rad51 oligomerization, facilitates filament formation, and protects filaments from destabilization by the helicase Srs2.
You're starting a #structuralbiology project and want to learn the basics. Please go there : www.biostine.fr/home-biostine/
Nadia Izadi-Pruneyre
Sarah Lambert's Lab
GL Moldovan Laboratory
Ewen Lescop
Jessica Andreani
Jessica Andreani
Francoise Ochsenbein
Francoise Ochsenbein
Francoise Ochsenbein
Ewen Lescop
www.biorxiv.org
Homologous recombination (HR) is essential for the repair of DNA double-strand breaks and the restart of stalled replication forks. A critical step in HR is the formation of Rad51 nucleofilaments, whi...
Author summary Protein-RNA interactions are crucial to many biological functions and can play a role in diseases. We adopted a computational strategy to analyze and compare experimental 3D structures ...
Our new preprint! (reposted with tags 🧬🧶)
We investigated how protein-RNA interface structure evolves by thoroughly analyzing the conservation of contacts among 2022 pairs of homologous interfaces. Work with Ikram Mahmoudi, Chloé Quignot, Carla Martins
